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Stains & CD markers
MyoD1

Nat Pernick, M.D.

Topic Completed: 1 June 2005

Minor changes: 2 July 2021

Copyright: 2002-2022, PathologyOutlines.com, Inc.

PubMed Search: MyoD1 [title]

Nat Pernick, M.D.
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Table of Contents
Definition / general | Interpretation | Positive staining - normal | Negative staining
Cite this page: Pernick N. MyoD1. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsmyod1.html. Accessed January 28th, 2022.
Definition / general
  • Myogenic transcriptional regulatory protein expressed early in skeletal muscle differentiation
  • Sensitive but not specific for rhabdomyosarcoma due to cytoplasmic and non-specific background staining (Am J Surg Pathol 2001;25:1150)
  • Stronger staining in alveolar vs. embryonal rhabdomyosarcomasar germ cell tumors (also other cells as indicated below)
Interpretation
  • Nuclear immunostaining
Positive staining - normal
  • Normal fetal muscle
Negative staining
  • Normal adult muscle
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