Pathology Outlines

Stains
Myogenin

Author: Nat Pernick, M.D.

Topic Completed: 1 June 2005

Revised: 7 March 2019

Copyright: 2002-2015, PathologyOutlines.com, Inc.

PubMed Search: Myogenin [title]

Page views in 2018: 3,731

Page views in 2019 to date: 3,431

Table of Contents

Definition / general | Microscopic (histologic) images | Positive staining - normal | Negative staining

Cite this page: Pernick N. Myogenin. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsmyogenin.html. Accessed October 19th, 2019.

Definition / general

Myogenic transcriptional regulatory protein expressed early in skeletal muscle differentiation
Sensitive and specific for rhabdomyosarcoma
Focal nuclear staining in desmoid tumors, infantile myofibromatosis, synovial sarcoma, infantile fibrosarcoma, entrapped atrophic or regenerative skeletal muscle (Am J Surg Pathol 2001;25:1150)

Microscopic (histologic) images

Hepatorenal embryonal rhabdomyosarcoma

Positive staining - normal

Normal fetal muscle

Negative staining

Normal adult muscle