Stains & molecular markers
Myogenin
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: Myogenin [title]
Myogenin
Author: Nat Pernick, M.D.
Topic Completed: 1 June 2005
Minor changes: 9 October 2020
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: Myogenin [title]
Cite this page: Pernick N. Myogenin. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsmyogenin.html. Accessed January 16th, 2021.
Definition / general
- Myogenic transcriptional regulatory protein expressed early in skeletal muscle differentiation
- Sensitive and specific for rhabdomyosarcoma
- Focal nuclear staining in desmoid tumors, infantile myofibromatosis, synovial sarcoma, infantile fibrosarcoma, entrapped atrophic or regenerative skeletal muscle (Am J Surg Pathol 2001;25:1150)
Positive staining - normal
- Normal fetal muscle
Negative staining
- Normal adult muscle
