Stains & molecular markers
Myogenin / myoglobin


Topic Completed: 1 June 2005

Minor changes: 8 March 2021

Copyright: 2002-2021, PathologyOutlines.com, Inc.

PubMed Search: Myogenin [title]

Nat Pernick, M.D.
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Table of Contents
Myogenin | Myoglobin
Cite this page: Pernick N. Myogenin / myoglobin. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsmyogenin.html. Accessed April 19th, 2021.
Myogenin
  • Myogenic transcriptional regulatory protein expressed early in skeletal muscle differentiation
  • Sensitive and specific for rhabdomyosarcoma
  • Focal nuclear staining in desmoid tumors, infantile myofibromatosis, synovial sarcoma, infantile fibrosarcoma, entrapped atrophic or regenerative skeletal muscle (Am J Surg Pathol 2001;25:1150)
  • Positive staining: normal fetal muscle;
  • Negative staining: normal adult muscle
Myoglobin
  • Oxygen binding protein
  • Positive staining: striated muscle (cardiac, skeletal); rhabdomyosarcoma, other tumors with skeletal muscle differentiation
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