Cite this page: Pernick N. N-myc. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsnmyc.html. Accessed January 16th, 2021.
Definition / general
- Also called MYCN, gene at 2p24
- Amplified gene forms double minutes and homogenously staining regions, and produces excessive N-myc protein
- Amplification (> 10 copies by Southern blot or FISH) associated with poor prognosis and 1p36.3 deletions