Stains & molecular markers
N-myc
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: N-myc [title]
N-myc
Author: Nat Pernick, M.D.
Topic Completed: 1 June 2005
Minor changes: 23 December 2020
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: N-myc [title]
Cite this page: Pernick N. N-myc. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsnmyc.html. Accessed January 16th, 2021.
Definition / general
- Also called MYCN, gene at 2p24
- Amplified gene forms double minutes and homogenously staining regions, and produces excessive N-myc protein
- Neuroblastoma:
- Amplification (> 10 copies by Southern blot or FISH) associated with poor prognosis and 1p36.3 deletions
Molecular / cytogenetics images
Contributed by LeicaBiosystems Amsterdam
MYCN (2p24) / AFF3 (2q11)
