Stains & molecular markers

Topic Completed: 1 June 2005

Minor changes: 23 December 2020

Copyright: 2002-2021,, Inc.

PubMed Search: N-myc [title]

Nat Pernick, M.D.
Page views in 2020: 255
Page views in 2021 to date: 13
Cite this page: Pernick N. N-myc. website. Accessed January 16th, 2021.
Definition / general
  • Also called MYCN, gene at 2p24
  • Amplified gene forms double minutes and homogenously staining regions, and produces excessive N-myc protein
  • Neuroblastoma:
    • Amplification (> 10 copies by Southern blot or FISH) associated with poor prognosis and 1p36.3 deletions
Molecular / cytogenetics images

Contributed by LeicaBiosystems Amsterdam

MYCN (2p24) / AFF3 (2q11)

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