Cite this page: Pernick N. p27. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsp27.html. Accessed January 22nd, 2021.
Definition / general
- Cyclin dependent kinase inhibitor leading to cell cycle arrest in G1 phase
- Member of Cip/Kip family of proteins
- Loss or reduced expression is associated with poor outcome in carcinoma of breast, prostate, GI tract and lung
- Nuclear stain