Stains & molecular markers

Topic Completed: 1 June 2005

Minor changes: 30 September 2020

Copyright: 2003-2021,, Inc.

PubMed Search: p27[title]

Nat Pernick, M.D.
Page views in 2020: 332
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Cite this page: Pernick N. p27. website. Accessed January 22nd, 2021.
Definition / general
  • Cyclin dependent kinase inhibitor leading to cell cycle arrest in G1 phase
  • Member of Cip/Kip family of proteins
  • Loss or reduced expression is associated with poor outcome in carcinoma of breast, prostate, GI tract and lung
  • Also called p27 kip1
  • Interpretation
    • Nuclear stain
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