Stains & CD markers
PCNA
Copyright: 2002-2023, PathologyOutlines.com, Inc.
PubMed Search: PCNA [title]
PCNA
Author: Nat Pernick, M.D.
Last author update: 1 June 2005
Last staff update: 23 July 2021
Copyright: 2002-2023, PathologyOutlines.com, Inc.
PubMed Search: PCNA [title]
Table of Contents
Definition / generalCite this page: Pernick N. PCNA. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainspcna.html. Accessed June 2nd, 2023.
Definition / general
- Proliferating Cell Nuclear Antigen
- Also called cyclin
- Nonhistone 36 kDa nuclear protein with a role in DNA synthesis, DNA repair, and cell cycle progression
- Coordinates synthesis of both leading and lagging strands at the replication fork during DNA replication
- Expression correlates with proliferation activity
