Stains & CD markers
ROS1



Last author update: 1 September 2013
Last staff update: 23 July 2021

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PubMed Search: ROS1[title]

Nat Pernick, M.D.
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Cite this page: Pernick N. ROS1. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsros1.html. Accessed August 17th, 2022.
Definition / general
Uses by pathologists
  • ROS1 immunostains are 100% sensitive and 92% specific for ROS1 rearrangements by FISH, making it an effective screening tool for lung adenocarcinoma (Am J Surg Pathol 2013;37:1441)
Microscopic (histologic) images

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Invasive ductal carcinoma (ROS1+, fig B)

Non small cell lung cancer

ROS1 rearranged lung tumors

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