Stains & molecular markers
SOX9


Topic Completed: 1 November 2013

Minor changes: 8 December 2020

Copyright: 2013-2021, PathologyOutlines.com, Inc.

PubMed Search: SOX9[title]

Nat Pernick, M.D.
Page views in 2020: 1,151
Page views in 2021 to date: 57
Cite this page: Pernick N. SOX9. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainssox9.html. Accessed January 19th, 2021.
Definition / general
  • Sex determining region Y (SRY)-related high mobility groupbox 9
  • Transcription factor linked to hedgehog pathways, plays a central role in development and differentiation of multiple cell lineages
  • Downstream molecule of beta-catenin
  • Master regulator of chondrogenesis
Clinical features
Uses by pathologists
Microscopic (histologic) images

Images hosted on other servers:

Duodenum:
normal mucosa
(figs D, E, F)

Duodenum:
nonampullary
adenoma
(figs D, E, F)

Duodenum:
nonampullary
adenocarcinoma
(figs D, E, F)

Liver: hepatocellular carcinoma and normal

Lung: normal and non small cell lung cancer


Skin: scalp

Skin: psoriasis,
keratoacanthoma,
carcinoma

Skin: TISH analysis

Testis: androgen insensitivity
and Sertoli cell only syndromes,
normal spermatogenesis

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