Stains & CD markers
Tyrosinase



Topic Completed: 1 May 2013

Minor changes: 18 June 2021

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PubMed Search: Tyrosinase[TI] review[ptyp]

Lauren N. Stuart, M.D., M.B.A.
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Cite this page: Stuart L. Tyrosinase. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainstyrosinase.html. Accessed October 24th, 2021.
Definition / general
  • Also called T311 (for immunohistochemistry)
  • Melanocyte specific antigen important in melanin synthesis and melanosome formation
  • Interpretation: cytoplasmic staining
Uses by pathologists
  • Identification of melanocytic neoplasms
Microscopic (histologic) images

Images hosted on other servers:

Normal skin prominent
melanocytes;
melanoma +
homogenous tumor cells

Melanoma (image 3, cytology)

Positive staining - normal
Positive staining - disease
Negative staining
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Image 01 Image 02