Stains & molecular markers
Urates / uric acid


Topic Completed: 1 June 2005

Minor changes: 24 December 2020

Copyright: 2003-2021, PathologyOutlines.com, Inc.

Nat Pernick, M.D.
Page views in 2020: 427
Page views in 2021 to date: 20
Cite this page: Pernick N. Urates / uric acid. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsurates.html. Accessed January 16th, 2021.
Definition / general
  • Uric acid crystals seen in acid urine
  • Urates present in tissue as sodium urate, but soluble in aqueous solutions and slightly soluble in weak alcoholic solutions, so tissue must be fixed in 95%/100% alcohol to prevent leaching of urates
  • Urates are stained black by GMS
  • Sodium urate crystals are birefringent on polarization
Microscopic (histologic) images

Image hosted on other servers:

Uric acid crystals, polarized, with red plate

Back to top
Image 01 Image 02