Stains & CD markers
Urates / uric acid
Copyright: 2003-2023, PathologyOutlines.com, Inc.
Urates / uric acid
Author: Nat Pernick, M.D.
Last author update: 1 June 2005
Last staff update: 12 August 2021
Copyright: 2003-2023, PathologyOutlines.com, Inc.
Cite this page: Pernick N. Urates / uric acid. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsurates.html. Accessed June 10th, 2023.
Definition / general
- Uric acid crystals seen in acid urine
- Urates present in tissue as sodium urate, but soluble in aqueous solutions and slightly soluble in weak alcoholic solutions, so tissue must be fixed in 95%/100% alcohol to prevent leaching of urates
- Urates are stained black by GMS
- Sodium urate crystals are birefringent on polarization
Microscopic (histologic) images
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Uric acid crystals, polarized, with red plate
