Stains & molecular markers

Topic Completed: 1 June 2005

Minor changes: 24 December 2020

Copyright: 2003-2021,, Inc.

Nat Pernick, M.D.
Page views in 2020: 427
Page views in 2021 to date: 24
Table of Contents
Definition / general
Cite this page: Pernick N. VEGF. website. Accessed January 20th, 2021.
Definition / general
  • Vascular Endothelial Growth Factor
  • Exists in 4 different homodimeric isoforms due to alternate splicing
  • Potent angiogenic growth factor that stimulates endothelial cell proliferation and induces microvessel permeability
  • Protein and mRNA are overexpressed in various tumors
  • May have prognostic significance in esophageal adenocarcinoma (Hum Pathol 2005;36:955)
Back to top
Image 01 Image 02