Table of ContentsDefinition / general | Case reports | Microscopic (histologic) description | Microscopic (histologic) images | Positive stains | Negative stains | Board review style question #1 | Board review style answer #1
Cite this page: Weisenberg E. Schwannoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stomachschwannoma.html. Accessed September 30th, 2023.
Definition / general
- Well circumscribed, benign nerve sheath tumor (also called neurilemmoma), much less common (~ 1 / 50) in stomach than GIST
Microscopic (histologic) description
- Well circumscribed but not encapsulated, with interlacing bundles of spindle cells and collagen
- Often nuclear pallisading, Verocay bodies, hyalinized vessels
- May have nuclear atypia, inflammatory cells, peripheral cuff of lymphoid aggregates
- No mitotic figures, no skenoid fibers, no epithelioid features
Microscopic (histologic) images
Board review style question #1
Which of the following describes the majority of schwannomas arising in the gastrointestinal tract?
- Both encapsulated and circumscribed
- Circumscribed but not encapsulated
- Encapsulated but not circumscribed
- Neither encapsulated nor circumscribed