Congenital adrenal hyperplasia

Testis and epididymis
Development
Congenital adrenal hyperplasia

Author: Turki Al-Hussain, M.D.

Topic Completed: 1 September 2012

Revised: 27 March 2019

Copyright: 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: Congenital adrenal hyperplasia [title] men

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Page views in 2020 to date: 19

Table of Contents

Definition / general

Cite this page: Al-Hussain T. Congenital adrenal hyperplasia. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/testisCAH.html. Accessed February 21st, 2020.

Definition / general

Autosomal recessive, due to various enzymatic defects that cause different patterns of synthesis of glucocortical, mineralocorticoid and sex hormone synthesis
Genetic males have cryptorchidism, viable Wolffian duct structures, female or ambiguous genitalia, no Müllerian duct structures
Testes resemble cryptorchid testes
May have bilateral Leydig cell hyperplasia with deficiencies of 21-hydroxylase, 11β hydroxylase, 17α hydroxylase, 3β hydroxysteroid dehydrogenase
Treat with corticosteroids or surgical excision of testes