Testis & epididymis
Development
Congenital adrenal hyperplasia


Topic Completed: 1 September 2012

Minor changes: 8 September 2020

Copyright: 2002-2020, PathologyOutlines.com, Inc.

PubMed Search: Congenital adrenal hyperplasia [title] men

Turki Al-Hussain, M.D.
Page views in 2019: 122
Page views in 2020 to date: 88
Table of Contents
Definition / general
Cite this page: Al-Hussain T. Congenital adrenal hyperplasia. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/testisCAH.html. Accessed September 23rd, 2020.
Definition / general
  • Autosomal recessive, due to various enzymatic defects that cause different patterns of synthesis of glucocortical, mineralocorticoid and sex hormone synthesis
  • Genetic males have cryptorchidism, viable Wolffian duct structures, female or ambiguous genitalia, no Müllerian duct structures
  • Testes resemble cryptorchid testes
  • May have bilateral Leydig cell hyperplasia with deficiencies of 21-hydroxylase, 11β hydroxylase, 17α hydroxylase, 3β hydroxysteroid dehydrogenase
  • Treat with corticosteroids or surgical excision of testes
Back to top
Image 01 Image 02