Testis & epididymis
Nonneoplastic lesions
Fibrous pseudotumor
Author: Swapnil U. Rane, M.D.
Topic Completed: 1 March 2015
Minor changes: 30 December 2020
Copyright: 2003-2021, PathologyOutlines.com, Inc.
PubMed search: Fibrous pseudotumor testis
Table of Contents
Definition / general | Terminology | Case reports | Radiology images | Clinical images | Gross description | Gross images | Microscopic (histologic) description | Microscopic (histologic) images | Differential diagnosisCite this page: Rane S. Fibrous pseudotumor. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/testisepidfibrpseudotumor.html. Accessed January 18th, 2021.
Definition / general
- Diffuse or localized, reactive fibromatous proliferation involving epididymis, tunica or spermatic cord
Terminology
- Other terms used:
- Fibroma
- Nonspecific peritesticular fibrosis
- Nodular fibrous periorchitis, chronic proliferative periorchitis, reactive periorchitis or pseudofibrous periorchitis
- Fibrous periorchitis (for diffuse lesions)
- Proliferative funiculitis
- Nodular pseudotumor (if forms a mass)
- Inflammatory fibropseudotumor or pseudotumor (if forms a mass)
- Peritesticular fibromatosis
- Fibrous mesothelioma
Case reports
- 28 year old man with paratesticular fibrous pseudotumor (J Med Case Rep 2013;7:225)
- Fibrous pseudotumor of epididymis and tunica vaginalis (Can J Urol 2006;13:3279)
- Paratesticular fibrous pseudotumor (Front Med 2014;8:484)
Radiology images
Images hosted on other servers:
MRI: polycyclic mass
Clinical images
Images hosted on other servers:
Intrascrotal mass
Gross description
- Can show diffuse band-like thickening, often encasing the testis
- Localized forms show single or multiple nodules, 2 mm to 9 cm
- Cut surface is usually firm, whitish
Gross images
Images hosted on other servers:
Pedunculated mass
Well demarcated margins
Microscopic (histologic) description
- Composed primarily of spindle cells with variable hyalinization and collagenization
- Variable component of lymphocytes, plasma cells, histiocytes and scattered eosinophils
- Nuclear atypia is usually absent, and if present is usually focal and restricted to the more cellular areas with more florid granulation tissue-like proliferation
- May have focal whorled arrangement, focal calcification and ossification
- Usually no mitoses
- No atypical mitoses
Microscopic (histologic) images
Images hosted on other servers:
Dense fibrotic tissue
Collagen rich hyalinized fibrotic tissue
CD3
IgG4
CD31
Differential diagnosis
- Sarcomas: generally are more cellular, with atypical mitoses and pleomorphism
