Testis and epididymis
Nonneoplastic lesions

Topic Completed: 1 March 2012

Revised: 15 December 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Epididymitis [title]

Rafael Jimenez, M.D.
Page views in 2019: 2,826
Page views in 2020 to date: 469
Cite this page: Jimenez R. Epididymitis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/testisepididymitis.html. Accessed February 21st, 2020.
Definition / general
  • Primary cause of epididymal obstruction
  • Usually related to cystitis, prostatitis or urethritis that spreads through vas deferens or lymphatics
  • May cause testicular ischemia and necrosis, later scarring and infertility with preservation of Leydig cells and preserved sexual activity
  • Acute disease: epididymis enlarged, covered with fibrin, may contain pus and rupture
  • Brucellosis: affects testis and epididymis in 20% of cases; has granulomatous appearance
  • Gonorrhea: affects epididymis before testis
  • Tuberculosis: may cause confluent caseation that spreads into testis and simulates malignancy; may cause scrotal fistula; should culture to rule out M. kansasii and M. avium-intracellulare
  • Children: usually gram negative rods, congenital genitourinary abnormality
  • Sexually active men age 35 or less: Chlamydia trachomatis, Neisseria gonorrhoeae
  • Men age 35+: E. coli, Pseudomonas and other urinary tract infection organisms
Microscopic (histologic) images

Images hosted on PathOut server:

Images contributed by Professor Venna Maheshwar, Drs. Kiran Alam and Anshu Jain, J. N. Medical College, India:

25 year old man with epididymal mass: filiarial epididymitis

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