Testis & epididymis
Development
Excurrent duct obstruction


Topic Completed: 1 September 2012

Minor changes: 8 September 2020

Copyright: 2002-2020, PathologyOutlines.com, Inc.

PubMed Search: Excurrent duct obstruction

Turki Al-Hussain, M.D.
Page views in 2019: 283
Page views in 2020 to date: 187
Cite this page: Al-Hussain T. Excurrent duct obstruction. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/testisexcurrentduct.html. Accessed September 20th, 2020.
Definition / general
  • Excurrent means distal to rete testis
  • Congenital or acquired
  • Occurs in 10% of biopsies for infertility
  • Associated with azoospermia, normal sized testes and active (but not necessarily normal) spermatogenesis (Am J Surg Pathol 1999;23:1546)
  • Congenital: agenesis or atresia of epididymis or vas deferens, atrophy from secretions in cystic fibrosis
  • Acquired: infection, sterilization, inadvertent surgical ligation of vas deferens
  • Partial excurrent duct obstruction is likely if sperm count is appreciably lower than that expected from biopsy
Microscopic (histologic) description
  • Active spermatogenesis, germ cell disorganization and sloughing
  • Variable interstitial fibrosis and sperm granulomas
  • No tubular basement membrane thickening
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