Excurrent duct obstruction

Testis and epididymis
Development
Excurrent duct obstruction

Author: Turki Al-Hussain, M.D.

Topic Completed: 1 September 2012

Revised: 27 March 2019

Copyright: 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: Excurrent duct obstruction

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Table of Contents

Definition / general | Microscopic (histologic) description

Cite this page: Al-Hussain T. Excurrent duct obstruction. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/testisexcurrentduct.html. Accessed February 20th, 2020.

Definition / general

Excurrent means distal to rete testis
Congenital or acquired
Occurs in 10% of biopsies for infertility
Associated with azoospermia, normal sized testes and active (but not necessarily normal) spermatogenesis (Am J Surg Pathol 1999;23:1546)
Congenital: agenesis or atresia of epididymis or vas deferens, atrophy from secretions in cystic fibrosis
Acquired: infection, sterilization, inadvertent surgical ligation of vas deferens
Partial excurrent duct obstruction is likely if sperm count is appreciably lower than that expected from biopsy

Microscopic (histologic) description

Active spermatogenesis, germ cell disorganization and sloughing
Variable interstitial fibrosis and sperm granulomas
No tubular basement membrane thickening