Thyroid & parathyroid

Thyroiditis

Lithium thyroiditis



Topic Completed: 1 March 2009

Minor changes: 16 September 2020

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PubMed Search: lithium thyroiditis

Shahid Islam, M.D., Ph.D.
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Cite this page: Islam S. Lithium thyroiditis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/thyroidlithiumthyroiditis.html. Accessed November 27th, 2021.
Definition / general
  • Lithium directly damages thyroid follicular cells, which releases thyroglobulin, which may be hydrolyzed to thyroxine, causing hyperthyroidism
Case reports
Microscopic (histologic) description
  • Small follicles with atrophy and minimal colloid; follicles contain desquamated follicular cells, macrophages and multinucleated giant cells; some giant cells contain birefringent calcium oxalate crystals (J Clin Pathol 1995;48:582)
Microscopic (histologic) images

Case #139

Differential diagnosis
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