Thyroid & parathyroid

Thyroiditis

Palpation thyroiditis



Topic Completed: 1 March 2009

Minor changes: 16 September 2020

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PubMed search: palpation thyroiditis

Shahid Islam, M.D., Ph.D.
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Cite this page: Islam S. Palpation thyroiditis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/thyroidpalpation.html. Accessed December 8th, 2021.
Definition / general
  • Common (85%+ of surgically resected thyroids) but clinically insignificant
Terminology
  • Also called multifocal granulomatous thyroiditis
Clinical features
Case reports
Treatment
  • Self limited, no treatment necessary
Gross description
  • Normal, or small foci of hemorrhage
Microscopic (histologic) description
  • Multiple small granulomas centered in disrupted follicles, composed of lymphocytes (usually T cells), macrophages (some foamy), occasional multinucleated giant cells associated with colloid breakdown, usually no necrosis, no neutrophils
Microscopic (histologic) images

Contributed by Andrey Bychkov, M.D., Ph.D.

Superficially
located nodule

Intrafollicular
granulomatous
reaction

Granulomatous folliculitis

Multinucleated giant cells



AFIP images

Histiocytes within follicle

Histiocytes are strongly lysozyme+



Images hosted on other servers:

Granuloma

Differential diagnosis
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