Smooth muscle tumors

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Minor changes: 12 August 2020

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PubMed search: lipoleiomyoma [title] uterus

Related topics: leiomyoma

Nat Pernick, M.D.
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Cite this page: Pernick N. Lipoleiomyoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/uterusleiomyomalipo.html. Accessed January 18th, 2021.
Definition / general
  • 2% of all leiomyomas; combination of leiomyoma and mature adipocytes with benign behavior (Int J Gynecol Pathol 2006;25:239)
  • Also includes neoplasms composed entirely of mature adipocytes
  • May be due to adipose metaplasia in leiomyomas; does not appear to be degenerative, since adipose tissue has low proliferative activity by Ki67 staining
  • May give rise to liposarcoma (Am J Surg Pathol 2011;35:221)
Case reports
Gross images

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Pale yellow to bright yellow appearance

Intramural yellow tumor

Microscopic (histologic) images

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Various images

Positive stains
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