Uterus
Smooth muscle tumors
Myxoid leiomyoma
Author: Nat Pernick, M.D.
Topic Completed: 1 August 2012
Minor changes: 12 August 2020
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed search: myxoid leiomyoma uterus
Related topics: leiomyoma
Table of Contents
Definition / general | Gross images | Microscopic (histologic) images | Differential diagnosisCite this page: Pernick N. Myxoid leiomyoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/uterusleiomyomamyxoid.html. Accessed January 17th, 2021.
Definition / general
- Islands of smooth muscle in myxoid connective tissue containing large vessels, but not infiltrative
- Small and bland nuclei (i.e. no atypia) and no mitotic activity
- Benign
- Myxoid leiomyosarcoma may arise in myxoid leiomyomas (Hum Pathol 2000;31:398)
Gross images
Images hosted on other servers:
Leiomyoma with extensive myxoid degeneration; cut surface
Leiomyoma with myxoid
degeneration in a 55
year old woman
Microscopic (histologic) images
AFIP images
ated fascicles of
smooth muscle cells
can be identified
Smooth muscle cells are
difficult to identify in
this field but were
numerous elsewhere
Images hosted on other servers:
myxoid degener-
ation in a 49 year
old woman (fig 7, 8)
Myxoid leiomyoma with
a marked pulmonary
edema pattern
Differential diagnosis
- Myxoid leiomyosarcoma: hypercellular, infiltrative, usually mild nuclear atypia
