Smooth muscle tumors
Myxoid leiomyoma

Topic Completed: 1 August 2012

Minor changes: 12 August 2020

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PubMed search: myxoid leiomyoma uterus

Related topics: leiomyoma

Nat Pernick, M.D.
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Cite this page: Pernick N. Myxoid leiomyoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/uterusleiomyomamyxoid.html. Accessed January 17th, 2021.
Definition / general
  • Islands of smooth muscle in myxoid connective tissue containing large vessels, but not infiltrative
  • Small and bland nuclei (i.e. no atypia) and no mitotic activity
  • Benign
  • Myxoid leiomyosarcoma may arise in myxoid leiomyomas (Hum Pathol 2000;31:398)
Gross images

Images hosted on other servers:

Leiomyoma with extensive myxoid degeneration; cut surface

Leiomyoma with myxoid
degeneration in a 55
year old woman

Microscopic (histologic) images

AFIP images

Only very attenu-
ated fascicles of
smooth muscle cells
can be identified

Smooth muscle cells are
difficult to identify in
this field but were
numerous elsewhere

Images hosted on other servers:

Leiomyoma with
myxoid degener-
ation in a 49 year
old woman (fig 7, 8)

Myxoid leiomyoma with
a marked pulmonary
edema pattern

Differential diagnosis
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Image 01 Image 02