Books for Pathologists
Molecular biology and Genetics
Revised: 19 September 2014
Copyright: (c) 2014, PathologyOutlines.com, Inc.
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Table of contents
By author New books Top books
By publisher: ARP Press ASCP CAP LWW WHO
Pathology Books: general surgical pathology anatomy autopsy bioterrorism board review breast cardiovascular cytopathology dermatopathology electron microscopy endocrine eye forensic GI GU grossing gynecologic head and neck hematopathology histology history IHC immunology informatics kidney lab medicine law liver lung mediastinum/serosa medical dictionaries medical writing microbiology molecular muscle neuropathology oncology other parasitology pediatric placenta soft tissue & bone statistics stem cells transfusion
Dermatology Books: cosmetic dermoscopy general infectious pediatric surgery tumors
Books by author: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Al-Mulla: Formalin-Fixed Paraffin Embedded Tissues
By Fahd Al-Mulla
2011 (1st ed), 295 pages, 57 illus, $139 list
Presenting an area of research that intersects with and integrates diverse disciplines, including genomics, epigenetics, proteomics, and cellular biology, among others, Formalin-Fixed Paraffin-Embedded Tissues: Methods and Protocols collects contributions from expert researchers in order to provide practical guidelines to this complex study. Compiled in order to provide researchers with up-to-date methodological information pertaining to the utilization of genomic, transcriptomic, and proteomic data in diagnosis, prognosis, and tailored therapy, the ultimate aim of this volume is to decipher diseases at a molecular level.
Albitar: Monoclonal Antibodies: Methods and Protocols
By Maher Albitar
2007 (1st ed), 267 pages, $100 list
Examines state-of-the-art methods that employ monoclonal antibodies, including generating mouse monoclonal antibodies through hybridoma technology, future methods for engineering recombinant and humanized antibodies, methods for engineering soluble Fc fusion protein and the use of antibodies and flow cytometry in the quantification of cell signaling proteins.
Appasani: Bioarrays: From Basics to Diagnostics
By Krishnarao Appasani
2007 (1st ed), 270 pages, $99 list
Provides an integrated and comprehensive collection of timely articles on the use of bioarray techniques in the fields of biotechnology and molecular medicine. The entire volume is broken into four sections – Bioarray Technology Platforms, Biomarkers and Clinical Genomics, Biomarker Identification Using Clinical Proteomics and Glycomics, and Emerging Technologies in Diagnostics – that create one well-integrated work. Particular emphasis is placed on DNA, protein, and carbohydrate biochips.
Behl: Cell Aging: Molecular Mechanisms and Implications for Disease
By Christian Behl and Christine Ziegler
2014, 108 pages, 34 illus, $46 list
Aging represents a physiological and per se non-pathological and multifactorial process involving a set of key genes and mechanisms being triggered by different endogenous and exogenous factors. Since aging is a major risk factor in connection with a variety of human disorders, it is increasingly becoming a central topic in biochemical and medical research. The plethora of theories on aging – some of which have been discussed for decades – are neither isolated nor contradictory but instead can be connected in a network of pathways and processes at the cellular and molecular levels.
Best: Molecular Genetics and Personalized Medicine
By Hunter Best
2012 (1st ed), 253 pages, 39 illus, $189 list
Molecular Genetics and Personalized Medicine highlights developments that have been made in the field of molecular genetics and how they have been applied clinically. It will serve as a useful reference for physicians hoping to better understand the role of molecular medicine in clinical practice. In addition, it should also prove to be an invaluable resource for the basic scientist that wants to better understand how advances in the laboratory are being moved from the bench to the bedside. All chapters are written by experts in their fields and include the most up to date medical information. The authors simplify complex genetic concepts and focus on practical patient related issues. The book will be of great value to pathologists, hematologists/oncologists, clinical geneticists, high-risk obstetricians, general practitioners, and physicians in all other medical specialties who utilize genetic testing to direct therapy.
Bruns: Fundamentals of Molecular Diagnostics
By David E Bruns, Edward R Ashwood and Carl A Burtis
2007 (1st ed), 288 pages, $60 list
This book offers an introduction to the newest, fastest-growing field in laboratory science. Explaining and clarifying the molecular techniques used in diagnostic testing, this text provides both entry-level and advanced information. It covers the principles of molecular biology along with genomes and nucleic acid alterations, techniques and instrumentation, and applications of molecular diagnostics.
Buckingham: Molecular Diagnostics: Fundamentals, Methods, & Clinical Applications
By Lela Buckingham and Maribeth L Flaws
2007 (1st ed), 462 pages, 312 illus, $60 list
This exceptional new resource introduces the fundamentals of nucleic acid biochemistry to students without previous molecular training, while also presenting advanced concepts for students learning at a higher level. And, your students will be better prepared for the future with discussions of general diagnostic procedures that emphasize the continuing emergence of new diagnostic technologies.
Cagle: Basic Concepts of Molecular Pathology
By Philip Cagle
2009 (1st ed), 224 pages, 53 illus, $80 list
The Molecular Pathology Library series was created to bridge the gap between traditional basic science textbooks in molecular biology and traditional medical textbooks for organ-specific diseases. Basic Concepts of Molecular Pathology is designed as a stand-alone book to provide the pathologist, clinician or radiologist with a concise review of the essential terminology, concepts and tools of molecular biology that are applied to the understanding, diagnosis and treatment of human diseases in the age of personalized medicine.
Cagle: Molecular Pathology of Lung Cancer
By Philip Cagle
2012 (1st ed), 281 pages, 46 illus, $189 list
As with other books in the Molecular Pathology Library Series, Molecular Pathology of Lung Cancer bridges the gap between the molecular specialist and the clinical practitioner, including the surgical pathologist who now has a key role in decisions regarding molecular targeted therapy for lung cancer. Molecular Pathology of Lung Cancer provides the latest information and current insights into the molecular basis for lung cancer, including precursor and preinvasive lesions, molecular diagnosis, molecular targeted therapy, molecular prognosis, molecular radiology and related fields for lung cancer generally and for the specific cell types. As many fundamental concepts about lung cancer have undergone revision in only the past few years, this book will likely be the first to comprehensively cover the new molecular pathology of lung cancer. It provides a foundation in this field for pathologists, medical oncologists, radiation oncologists, thoracic surgeons, thoracic radiologists and their trainees, physician assistants, and nursing staff.
Campbell: Cancer Cytogenetics: Methods and Protocols
By Lynda Campbell
2011 (1st ed), 283 pages, $119 list
Cancer Cytogenetics: Methods and Protocols presents eminently practical key cytogenetic and FISH techniques for every stage of diagnostic service. Experts in the field describe detailed cytogenetic analysis methods, fluorescence in situ hybridization and array methods currently being applied to investigate and diagnose different varieties of cancer. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, and step-by-step, readily reproducible laboratory protocols. The authors of the various chapters have also provided extensive notes to guide individuals who are new to these methods through the pitfalls that bedevil all such testing. Authoritative and accessible, Cancer Cytogenetics: Methods and Protocols serves as an ideal guide to scientists of all backgrounds, allowing them to either establish new techniques in their laboratories or find the different variations of standard methods helpful in improving their results.
Chen: Atlas of Genetic Diagnosis and Counseling
By Harold Chen
2012 (2nd ed), 2284 pages, 2018 illus, $699 list
The author provides a detailed outline for each disorder, describing its genetics, basic defects, clinical features, diagnostic tests, and counseling issues, including recurrence risk, prenatal diagnosis, and management. Numerous color photographs of prenatal ultrasounds, imagings, cytogenetics, and postmortem findings illustrate the clinical features of patients at different ages, patients with varying degrees of severity, and the optimal diagnostic strategies. The disorders cited are supplemented by case histories and diagnostic confirmation by cytogenetics, biochemical, and molecular techniques, when available. The Atlas of Genetic Diagnosis and Counseling will help all physicians to understand and recognize genetic diseases and malformation syndromes and better evaluate, counsel, and manage affected patients. In this new edition, 47 additional genetic disorders are added, as well as extensive updates made to the previous disorders. New illustrations, as previous edition, will be supplemented by case and family history, clinical features, and laboratory data, especially molecular confirmation.
Cheng: Molecular Genetic Pathology
By Liang Chen
2013 (2nd ed), 1157 pages, 442 illus, $180 list
Molecular Genetic Pathology, Second Edition presents up-to-date material containing fundamental information relevant to the clinical practice of molecular genetic pathology. Fully updated in each area and expanded to include identification of new infectious agents (H1N1), new diagnostic biomarkers and biomarkers for targeted cancer therapy. This edition is also expanded to include the many new technologies that have become available in the past few years such as microarray (AmpliChip) and high throughput deep sequencing, which will certainly change the clinical practice of molecular genetic pathology. Part I examines the clinical aspects of molecular biology and technology, genomics. Poharmacogenomics and proteomics, while Part II covers the clinically relevant information of medical genetics, hematology, transfusion medicine, oncology, and forensic pathology. Supplemented with many useful figures and presented in a helpful bullet-point format, Molecular Genetic Pathology, Second Edition provides a unique reference for practicing pathologists, oncologists, internists, and medical genetisists. Furthermore, a book with concise overview of the field and highlights of clinical applications will certainly help those trainees, including pathology residents, genetics residents, molecular pathology fellows, internists, hematology/oncology fellows, and medical technologists in preparing for their board examination/certification.
Coleman: Basic Concepts in Molecular Medicine
By William Coleman
2012 (1st ed), 100 illus, 350 pages, $79 list
Volume 1 begins with an introduction covering the concepts of molecular medicine and personalized medicine. Subsequent chapters cover the topics of genomics, transcriptomics, epigenomics, and proteomics, as the tools of molecular pathology and foundations of molecular medicine. These chapters are followed by a series of chapters that provide overviews of molecular medicine as applied broadly to neoplastic, genetic, and infectious diseases, as well as a chapter on molecular diagnostics (how we harness diagnostic clues to guide treatment). The volume concludes with a chapter that delves into the promise of molecular medicine in the personalized treatment of patients with complex diseases, along with a discussion of the challenges and obstacles to personalized patient care.
Coleman: Essential Concepts in Molecular Pathology
By William Coleman
2010 (1st ed), 462 pages, $70 list
This streamlined "essential" version of the Molecular Pathology (2009) textbook extracts key information, illustrations and photographs from the main textbook in the same number and organization of chapters. It is aimed at teaching students in courses where the full textbook is not needed, but the concepts included are desirable (such as graduate students in allied health programs or undergraduates). It is also aimed at students who are enrolled in courses that primarily use a traditional pathology textbook, but need the complementary concepts of molecular pathology (such as medical students). Further, the textbook will be valuable for pathology residents and other postdoctoral fellows who desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school.
Coleman: Molecular Pathology: The Molecular Basis of Human Disease
By William Coleman
2009 (1st ed), 664 pages, $100 list
Molecular Pathology is appropriate as a classroom teaching tool for medical students, biomedical graduate students, and some allied health students. In addition, it should be used as a reference book for practicing basic scientists and physician scientists that perform disease-related research. Further, this textbook will be valuable for pathology residents and other postdoctoral fellows who need to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school.
Coppola: Molecular Pathology and Diagnostics of Cancer
By Domenico Coppola
2013 (1st ed), 450 pages, $209 list
Molecular pathology is based on the emergence of new techniques that greatly enhance the diagnostic accuracy when facing with challenging differential diagnoses. In addition, new molecular techniques are entering the clinical arena for their value in predicting therapy response and tumor prognosis. This book provides a guide for the practicing pathologist and for both pathology residents and fellows during the daily sign-out of challenging cases. The book is organized by anatomical systems and provides a detailed description of molecular tests that may help in the diagnosis. Furthermore, a description of the current molecular tests required to identify patients for treatment is offered. The application of molecular pathology techniques to the clinical practice has already shown its usefulness and the number of such tests is growing exponentially as more molecular targets are discovered. Molecular Pathology and Diagnostics of Cancer will give practicing and training pathologists an up-to date resource to guide the correct management of pathology cases requiring molecular testing.
Daoud: Cancer Proteomics
By Sayed S Daoud
2007 (1st ed), 300 pages, $125 list
This book provides the reader with broad perspectives and breadth of knowledge on current topics related to the use of proteomic strategies in cancer therapy as well as anticipated challenges that may arise from its application in daily practice.
Dudek: High-Yield Cell and Molecular Biology
By Ronald Dudek
2010 (3rd ed), 151 pages, $33 list
High-Yield Cell and Molecular Biology, Third Edition provides the essential information needed for USMLE Step 1 review and course study. It covers current cell and molecular biology techniques and principles with a clinical focus-what a physician needs to know to understand, diagnose, and treat human disease. Molecular biology is often taught within various courses such as biochemistry, microbiology, and histology; thus, a consolidated review book in molecular biology is especially helpful in preparing for the USMLE Step 1. This edition had been streamlined to remove content covered in other High Yield books such as histopathology and microbiology. Images have been placed closer to the appropriate text. New figures include DNA melting curve and flow cytometry. Features: NEW! edited and streamlined to remove content covered in other High Yield books (e.g., Histopathology, Microbiology); NEW! improved layout of art and text to place fugures closer to the appropriate text; NEW! new figures to Cover DNA melting curve and flow ctyometry; covers current molecular biology techniques and principles with a clinical focus - what a physician needs to know to diagnose, understabd and treat human disease; defines the line between molecular biolgy and genetics; this book and High-Yield Genetics by the same author have been written as a complementary pair & includes cell biology, but no basic traditional histology..
Dunphy: Molecular Pathology of Hematolymphoid Diseases
By Cherie Dunphy
2010 (1st ed), 639 pages, $199 list
In the Molecular Pathology Library series the basic science and the technology is integrated with the medical perspective and clinical application. Each book in the series is divided according to neoplastic and non-neoplastic diseases for each of the organ systems traditionally associated with medical subspecialties. Each book in the series is organized to provide specific application of molecular pathology to the pathogenesis, diagnosis and treatment of neoplastic and non-neoplastic diseases specific to each organ system. These broad section topics are broken down into succinct chaptersto cover a very specific disease entity. The chapters are written by established authorities on the specific topic from academic centers around the world.
Giordano: Molecular Pathology of Gynecologic Cancer
By Antonio Giordano, Alessandro Bovicelli and Robert J Kurman
2007 (1st ed), 313 pages, 41 illus, $175 list
Molecular Pathology of Gynecologic Cancer presents a focused educational experience featuring various perspectives and expertise in the emerging are of molecular biology with correlation of morphology in gynecologic cancer.
Harbers: Tag-based Next Generation Sequencing
By Matthias Harbers, Guenter Kahl
2012 (1st ed), 608 pages, $176 list
Tag-based approaches were originally designed to increase the throughput of capillary sequencing, where concatemers of short sequences were first used in expression profiling. New Next Generation Sequencing methods largely extended the use of tag-based approaches as the tag lengths perfectly match with the short read length of highly parallel sequencing reactions. Tag-based approaches will maintain their important role in life and biomedical science, because longer read lengths are often not required to obtain meaningful data for many applications. Whereas genome re-sequencing and de novo sequencing will benefit from ever more powerful sequencing methods, analytical applications can be performed by tag-based approaches, where the focus shifts from 'sequencing power' to better means of data analysis and visualization for common users. Today Next Generation Sequence data require powerful bioinformatics expertise that has to be converted into easy-to-use data analysis tools. The book's intention is to give an overview on recently developed tag-based approaches along with means of their data analysis together with introductions to Next-Generation Sequencing Methods, protocols and user guides to be an entry for scientists to tag-based approaches for Next Generation Sequencing.
Highsmith: Molecular Diagnostics: 12 Tests That Changed Everything
By W. Edward Highsmith Jr.
2013, 252 pages, 41 illus, $189 list
Molecular Diagnostics: 12 Tests That Changed Everything focuses on specific laboratory tests and emphasizes how the availability of these tests has altered how clinicians treat their patients. Presented as a standard outline, each chapter focuses on a specific molecular test and provides background on the test and its clinical applications. Continuing with some discussion on how the test is done, interpreted, and used clinically, each chapter then concludes with a discussion of how that test has changed the way medicine is practiced with respect to the disease or condition in question.
Hilario: Protocols for Nucleic Acid Analysis by Nonradioactive Probes
By Elena Hilario
2010 (2nd ed), 321 pages, $129 list
Protocols for Nucleic Acid Analysis by Non-radioactive Probes, Second Edition provides a firm background on the basic preparative protocols required for the analysis of nucleic acids by nonradioactive methods. Presenting the methodologies using amazing new applications, this volume offers guide chapters on nucleic acid extractions, preparation of nucleic acid blots, and labeling of nucleic acids with nonradioactive haptens. New fluorescent techniques such as Real Time PCR and microarrays are also included, allowing users to get a nonradioactive protocol implemented in the laboratory with minimum adaptation required and fastest time to results. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Homeister: Molecular and Translational Vascular Medicine
By Jonathon W. Homeister and Monte S. Willis
2012 (1st ed), 349 pages, 42 illus, $209 list
Molecular and Translational Vascular Medicine will serve as a state-of-the-art resource for physicians and translational medical researchers alike who are interested in the rapidly evolving field of vascular medicine. The text provides new insight into the basic mechanisms of classic vascular pathophysiologic processes like angiogenesis, atherosclerosis, thrombosis, and vasculitis. Furthermore, it covers new areas of investigation including the role of the ubiquitin proteasome system in vascular disease, endothelial progenitor cells for disease treatment, and the genetic basis of thoracic aortic aneurysms. Lastly, this volume includes sections on the newly emerging field of therapeutic angiogenesis, and the developing technology of nanoparticle-based imaging and therapeutic treatment of the diseased vasculature. All chapters are written by established experts in their fields, including pathologists, cardiovascular surgeons, and internists as well as translational biomedical researchers in a wide range of disciplines. While comprehensive, the material is presented in a manner that simplifies the complex pathophysiologic mechanisms that underlie common vascular diseases. Molecular and Translational Vascular Medicine will be of great value to a broad audience including internists, cardiovascular and vascular surgeons, pathologists, residents and fellows, as well as translational biomedical researchers.
Hu: Modern Clinical Molecular Techniques
By Peter Hu
2012 (1st ed), 449 pages, $219 list
This timely book covers the need to know clinical practices for all those involved in molecular laboratory science. The field of molecular medicine is evolving at an astounding speed. Propelled by the new insights and technologies, advances are being made at an unprecedented rate. With dual measure given to today’s breakthroughs, this book is a collection of the most current practices relevant to the clinical molecular laboratorian. It begins with an introductory section on techniques and procedure. It then presents four separate sections on infectious disease, oncology, pre/post-natal, and identity testing, with specific chapters clearly outlining clinical protocols used in daily practice. Modern Clinical Molecular Techniques cuts to the heart of what is essential for the practicing molecular laboratory scientist. It is an outstanding resource for those operating within or looking to set up a clinical molecular laboratory.
Hunt: Molecular Pathology of Endocrine Diseases
By Jennifer Hunt
2010 (1st ed), 618 pages, 18 illus, $169 list
The Molecular Pathology Library Series fills the gap between basic science and clinical application. Each user-friendly reference brings together diverse topics about molecular pathogenesis, diagnosis and treatment in one volume. The series serves physicians and healthcare providers in multiple disciplines who need to understand and apply molecular diagnostics and therapy to patient care; residents and fellows who integrate molecular medicine into their curricula and future practice; and basic and translational researchers who must define the impact of their research on clinical medicine.
Jorgensen: Molecular Diagnostics
By Jan Jorgensen
2010, 351 pages, $160 list
This unique book provides a thorough overview of developing molecular cancer diagnostic assays, which are the prerequisites for optimal solutions within personalized cancer medicine. The book takes the reader through definitions of the pharmacodiagnostic concept, historical perspectives of the early steps into molecular cancer diagnostics linked to therapy, the basis of different diagnostic molecular techniques, ongoing research, drug-diagnostic co-development, assay validation, clinical trial methodology, regulatory issues around pharmacodiagnostics and future aspects within personalized cancer medicine.
Keren: Protein Electrophoresis in Clinical Diagnosis
By David Keren
2012, 256 pages, 309 illus, $165 list
Since the publication of High-Resolution Electrophorsesis and Immunofixation 2e, there have been ever-increasing advances in the analyses of proteins, by electrophoresis in particular. Protein Electrophoresis in Clinical Diagnosis shows the changes in both techniques and interpretation, presenting a comprehensive review of serum protein techniques, immunofixation techniques, approaches to pattern interpretation, and pattern interpretation in both cerebralspinal fluid and urine. Conditions associated with Monoclunal Gammopathies are considered, as are the appropriate strategies for their detection.
Knudsen: Cancer Diagnostics with DNA Microarrays
By Steen Knudsen
2006 (1st ed), 208 pages, $125 list
Authored by an international authority in the field, Cancer Diagnostics with DNA Microarrays is a complete reference work on the rapidly growing use of DNA microarray data in the diagnosis of and treatment planning for a large number of human cancers.
Korenberg: Microarray Data Analysis: Methods and Applications
By Michael J Korenberg
2007 (1st ed), 312 pages, $100 list
An up-to-date guide on microarray data analysis, including genomic signal processing, predictive models of gene regulation, analysis of comparative genomic hybridization data on cDNA microarrays, and interpreting microarray results with gene ontology and MeSH ontology.
Kumar: The Molecular Biology of Chronic Heart Failure
By Dhavendra Kumar
2013 (1st ed), 88 pages, $40 list
The clinical syndrome of chronic heart failure (CHF) is the hallmark of progressive cardiac decompensation, one of the most common chronic medical conditions that affect around 2% of the adult population worldwide irrespective of ethnic and geographic origin (Anonymous). Apart from ischemic heart disease, hypertension, infection, and inflammation, several other etiologic factors account for irreparable and irreversible myocardial damage leading to heart failure (HF). Genetic and genomic factors are now increasingly identified as one of the leading underlying factors (Arab and Liu 2005). These factors may be related to pathogenic alterations (mutation or polymorphism) within specific cardiac genes, mutations in genes incorporating single or multiple molecular pathways (protein families) relevant to cardiac structure and/or function, genetic or genomic polymorphisms of uncertain significance (gene variants, single-nucleotide polymorphisms (SNPs), and copy number variations (CNVs)), and epigenetic or epigenomic changes that influence cardiac gene functions scattered across the human genome. Recent genetic and genomic studies in both systolic and diastolic ventricular dysfunction, the hallmark of CHF, have revealed a number of mutations in genes belonging to specific cardiac protein families.
Leonard: Molecular Pathology in Clinical Practice
By Debra G B Leonard
2006 (1st ed), 624 pages, 189 illus, $189 list
Molecular Pathology In Clinical Medicine is an authoritative, comprehensive textbook that provides the general pathologist in clinical practice, as well as residents and fellows during their training, with the current standard in molecular testing.
Leonard: Molecular Pathology in Clinical Practice: Genetics
By Debra Leonard
2008 (1st ed), 250 pages, 67 illus, $80 list
Molecular Pathology Testing in Clinical Practice: Genetics is an authoritative and comprehensive guide that provides the general pathologist in clinical practice, as well as residents and fellows during their training, with the current standard in molecular genetic testing. The book integrates the latest advancements in the field with the basic principles and practical applications.
Leonard: Quick Compendium Companion for Molecular Pathology
By George Leonard, Frank Zuehl, Daniel Mais
2009, 208 pages, $83 list
As molecular pathology continues to become a growth industry, it is more important than ever to keep pace with advances in this expanding field. The original Quick Compendium of Molecular Pathology is an essential resource for board exam preparation and for maintaining competency in molecular pathology.
Lo: Clinical Applications of PCR
By Y.M. Dennis Lo
2006 (2nd ed), 210 pages, $149 list
In this updated second edition, leading researchers apply molecular diagnostics to the many recent advances that have occurred in polymerase chain reaction( PCR)-based technologies. Highlights include real-time PCR, which allows the technique to be performed in a quantitative manner with improved sensitivity, robustness, and resilience to carryover contamination, mass spectrometric analysis of nucleic acids, and circulating cell-free nucleic acids in plasma. The authors apply these innovations to a broad spectrum of applications, including gene expression, methylation, trace molecule, gene dosage, and single cell analysis.
Lupski: Genomic Disorders: The Genomic Basis of Disease
By James R Lupski and Pawel T Stankiewicz
2006 (1st ed), 426 pages, $145 list
A grand summary and synthesis of the tremendous amount of data now available in the post genomic era on the structural features, architecture, and evolution of the human genome. The authors demonstrate how such architectural features may be important to both evolution and to explaining the susceptibility to those DNA rearrangements associated with disease.
Mais: Quick Compendium of Molecular Pathology
By Daniel D Mais and Mary Nordberg
2008 (3rd ed), 320 pages, $125 list
This new quick compendium provides an accessible review of genetics, genetic diseases, and diagnostic molecular pathology. Practicing general pathologists, with relatively little effort, will understand the nuts and bolts and most current practices of this burgeoning field.
Monga: Molecular Pathology of Liver Diseases
By Satdarshan Monga
2010 (1st ed), 954 pages, $279 list
Cellular and Molecular Pathology of the Liver is extensive, complex and ranges from the understanding the basic molecular mechanisms that dictate everything from liver homeostasis to liver disease. Molecular Pathology of the liver is complicated due to some of the important functions inherent and unique to the Liver, including its innate ability to regenerate and the multitude of functions it plays for the wellbeing of an organism. With all this in mind, Molecular Pathology of Liver Diseases is organized in different sections, which will coherently and cohesively present the molecular basis of hepatic physiology and pathology. The first two sections are key to understanding the liver anatomy and physiology at a cellular level and go on to define the molecular mechanics in various liver cell types. These sections also cover the existing paradigms in liver development, regeneration and growth. The next section is key to understanding the Molecular Pathology unique to liver diseases and associated phenotypes. The final sections are geared towards the existing knowledge of the molecular basis of many common and uncommon liver diseases in both neoplastic and non-neoplastic areas including pathologies associated with intra-hepatic and extra-hepatic biliary tree. Thus, this textbook is a one-stop reference for comprehending the molecular mechanisms of hepatic pathobiology. It is clearly unique in its format, readability and information and thus will be an asset to many in the field of Pathology and other disciplines.
Murphy: Molecular Diagnostics in Dermatology and Dermatopathology
By Michael Murphy
2011 (1st ed), 491 pages, $239 list
"Molecular Diagnostics in Dermatology and Dermatopathology" presents the basics of molecular biology and molecular diagnostic methods most commonly used in the clinical laboratory, with an emphasis on the concepts and testing most relevant to dermatological diseases. Topics include the integration of newer diagnostic and prognostic techniques with 'traditional' histologic approaches, and discussions of regulatory, ethical, legal, economic issues and 'newer' technologies. This important diagnostic tool outlines the clinically relevant uses (i.e.; diagnostic, staging and/or prognostic) applications of these techniques in the field of dermatology. Molecular studies that investigate the pathogenesis of skin diseases will be excluded, unless they also have a direct diagnostic utility. The book will be of interest to practicing pathologists, dermatology and pathology residents, dermatologists, and dermatopathologists.
Netto: Genomic Applications in Pathology
By George Jabboure Netto, Iris Schrijver
2014 (1st ed), 718 pages, $239 list
Genomic Applications in Pathology provides a state-of-the art review of the scientific principles underlying next generation genomic technologies and the required bioinformatics approaches to analyses of the daunting amount of data generated by current and emerging genomic technologies. Implementation roadmaps for various clinical assays such as single gene, gene panels, whole exome and whole genome assays are discussed together with issues related to reporting, including the pathologist’s role in interpretation and clinical integration of genomic tests results. Genomic applications for site-specific solid tumors and hematologic neoplasms are detailed, as well as genomic applications in pharmacogenomics, inherited genetic diseases, and infectious diseases. The latest iteration of practice recommendations and guidelines in genomic testing, put forth by stakeholder professional organizations such as the Association for Molecular Pathology and the College of American Pathologists, are also discussed in the volume, as well as regulatory issues and laboratory accreditation related to genomic testing.
Nielsen: Serial Analysis of Gene Expression (SAGE): Methods and Protocols
By Kare Nielsen
2010 (1st ed), 218 pages, $119 list
This book facilitates the introduction of SAGE into the laboratory and provides a framework for interpreting and comparing data derived from SAGE experiments. SAGE studies encompass 50,000 tags and can provide detailed knowledge of the 2000 most highly expressed genes in the tissue sample. The SAGE protocols presented are detailed, fully annotated, and tested, and are all written by experienced SAGE researchers from around the world.
Nuovo: In Situ Molecular Pathology and Co-Expression Analyses
By Gerard Nuovo
2013, 298 pages, $125 list
In Situ Molecular Pathology and Co-Expression Analyses explains, in easy-to-understand language, simplified ways of understanding and performing in situ hybridization and immunohistochemistry tests. The book also focuses on straightforward protocols used to simultaneously detect two or more proteins/nucleic acids within intact tissue by doing co-expression analyses.
Pecorino: Molecular Biology of Cancer
By Lauren Pecorino
2012 (3rd ed), 352 pages, $51 list
The third edition of The Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers a fresh approach to the study of the molecular basis of cancer, by showing how our understanding of the defective mechanisms that drive cancer is leading to the development of new targeted therapeutic agents.
Pfeifer: Molecular Genetic Testing in Surgical Pathology
By John Pfeifer
2005 (1st ed), 473 pages, $179 list
Written by experts from Washington University School of Medicine, this text is a thorough review of the specific molecular genetic techniques that can provide diagnostically useful molecular genetic information on tissue samples—including cytogenetics, fluorescence in situ hybridization (FISH), PCR, electrophoresis and hybridization analysis, DNA sequence analysis, and microarrays. The first part of the book describes each technique, indicates its advantages, disadvantages, capabilities, and limitations, and systematically addresses sensitivity and specificity issues. Subsequent chapters, organized by organ system, detail the specific applications of these tests in surgical pathology. More than 150 full-color and black-and-white illustrations complement the text.
Platero: Molecular Pathology in Drug Discovery and Development
By J. Suso Platero
2009 (1st ed), 373 pages, $115 list
Molecular pathology offers tools and techniques that can greatly enhance the drug discovery and development process, helping to make the promises of personalized medicine a reality. Molecular Pathology in Drug Discovery and Development provides an unmatched guide to this cutting-edge discipline and its applications to pharmaceutical science. With contributions from leading lights in drug discovery, drug development, and molecular pathology balanced by a consistent editorial approach, this reference offers both an overview of molecular pathology and a close look at the methods as they are applied to the process of drug discovery and development.
Roy: The Molecular Biology of Cadherins
By Frans Roy
2013 (1st ed), 488 pages, $171 list
This volume of Progress in Molecular Biology and Translational Science focuses on the most recent research surrounding Cadherins from top experts in the field.
Russo: Diagnostic, Prognostic and Therapeutic Value of Gene Signatures
By Antonio Russo
2011 (1st ed), 193 pages, 28 illus, $189 list
Diagnostic, Prognostic and Therapeutic Value of Gene Signatures provides readers a useful and comprehensive resource about the range of applications of microarray technology in oncological diseases. Topics covered include gene signatures and soft tissue sarcomas, prognostic relevance of breast cancer signatures, gene expression profiling of colorectal cancer and liver metastasis, gene signatures in GISTs, CNVs and gene expression profiles in pancreatic cancer, and gene signatures in head/neck, lung and gastric tumors.
Schrijver: Diagnostic Molecular Pathology in Practice
By Iris Schrijver
2011 (1st ed), 350 pages, 60 illus, $70 list
This entirely case-based book covers a broad cross-section of the practical issues frequently encountered in the day-to-day activities of a molecular genetic pathologist. The book is divided into four sections on the principal areas addressed in molecular genetic pathology (MGP): inherited diseases, hematopathology, solid tumors, and infectious diseases. The topics covered by the cases in each section include test selection, qualitative and quantitative laboratory techniques, test interpretation, prognostic and therapeutic considerations, ethical considerations, technical troubleshooting, and result reporting. This book will be ideal for trainees in MGP and clinical molecular genetics who require a practice-based preparation for board examinations. It will also be very useful for residents and fellows in medical specialties to which MGP is pertinent, and for practicing pathologists who want to learn more about the current practice of molecular diagnostics.
Sepulveda: Molecular Pathology of Neoplastic Gastrointestinal Diseases
By Antoniaa Sepulveda
2013 (1st ed), 287 pages, $189 list
Molecular Pathology of Neoplastic Gastrointestinal Diseases reviews the molecular aspects that characterize the spectrum of neoplastic conditions that affect the gastrointestinal tract, providing the reader with current up-to-date knowledge. For each disease entity chapters provide reviews on: the molecular basis of the individual diseasemolecular testing approaches currently available or in development for diagnosis or for gene target characterization for selective targeted therapiesrecommended guidelines for clinical application of molecular tests are included whenever availablemolecular testing for hereditary predisposition or disease riskanimal models and cell culture models of disease
Stanta: Guidelines for Molecular Analysis in Archive Tissues
By Giorgio Stanta
2011 (1st ed), 339 pages, 46 illus, $139 list
A huge amount of fixed and paraffin-embedded tissue is stored in every hospital. This is very precious material that can be used for translational research and for diagnostics. The molecular methods employed for analysis of these tissues are similar to the usual molecular biology and proteomics methods, but reliable results can be obtained only if specific steps are followed with great care. This book provides detailed and precise guidelines for molecular analysis of archive tissues and will serve as an invaluable aid for researchers and pathologists involved in translational research and diagnostics. Clear notes and explanations are included to simplify use of the protocols for the less experienced. The authors are a group of acknowledged experts who have developed the described methods and validated them within the European project "Archive Tissues: Improving Molecular Medicine Research and Clinical Practice - IMPACTS", which has involved 21 leading institutions in 11 countries.
Tan: Principles of Molecular Diagnostics and Personalized Cancer Medicine
By Dongfeng Tan and Henry T. Lynch
2013, 992 pages, $249 list
The role of molecular genetics in the treatment of malignancy continues to grow at an astonishing rate. Today’s subspecialized multidisciplinary approach to oncology has incorporated advances in targeted molecular therapy, prognosis, risk assessment, and prevention—all based at least in part on molecular diagnostics and imaging. Inside this cutting-edge resource, readers will explore broad, comprehensive perspectives on the current trends in molecular diagnosis of cancer and personalized cancer medicine. Authoritative discussions share insights from noted experts in cancer research, clinical trials, molecular diagnostics, personalized therapy, bioinformatics, and federal regulations. From the basic mechanisms of carcinogenesis to the most advanced molecular screening, staging, and treatment technologies, readers will discover clear and straightforward discussions directly relevant to patient diagnosis and care.
Thongboonkerd: Proteomics of Human Body Fluids
By Visith Thongboonkerd
2010 (1st ed), 546 pages, $185 list
This volume is the first collection of applications of proteomics to analyze various human body fluids. Proteomics of Human Bodyfluids consists of two parts. The first provides basic principles and strategies for proteomic analysis of human body fluids. The second offers more details regarding methodologies and recent findings and clinical applications of each specific type of human body fluids.
Tubbs: Cell and Tissue Based Molecular Pathology
By Raymond R Tubbs and Mark H Stoler
2008, 452 pages, 600 illus, $159 list
This volume packs today's most essential cell and tissue base molecular pathology into a compact, high-yield format! It focuses on the state of the art in practical validated molecular diagnostics as applied across the fields of surgical pathology and cytology.
Weinberg: The Biology of Cancer
By Robert Weinberg
2013, 960 pages, 600 illus, $150 list
The Biology of Cancer is a textbook for students studying the molecular and cellular bases of cancer at the undergraduate, graduate, and medical school levels. The principles of cancer biology are presented in an organized, cogent, and in-depth manner. The clarity of writing, supported by an extensive full-color art program and numerous pedagogical features, makes the book accessible and engaging. The information unfolds through the presentation of key experiments that give readers a sense of discovery and provide insights into the conceptual foundation underlying modern cancer biology.
Yousef: Molecular Testing in Cancer
By George M. Yousef and Serge Jothy
2014, 442 pages, 87 illus, $176 list
Molecular Testing in Cancer provides a state of the art review of clinically relevant molecular pathology in cancer. The book provides a brief, easy to read review of commonly employed diagnostic molecular techniques including recently developed "next generation" analytic tools, and offers a system-based run-through of the utility of molecular testing in individual cancer types, as well as reviewing current markers in cancer diagnosis, prognosis, and management. The volume also provides a prospective for the future which includes recently characterized and emerging biomarkers.
End of Molecular biology and Genetics books
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