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Thyroid gland


Minor changes: 1 December 2020

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Table of contents
General:anatomy books embryology features to report frozen section grossing histology staging recommended literature references-additional WHO classification
Cytology
Fine needle aspiration:FNA-general molecular testing in FNA ultrasound
Bethesda system:diagnostic categories adequacy nondiagnostic / unsatisfactory benign atypia of undetermined significance / follicular lesion of undetermined significance follicular neoplasm Hürthle cell neoplasm suspicious for malignancy malignant
Congenital / metabolic anomalies:aplasia / hypoplasia branchial pouch / cleft anomalies DiGeorge syndrome ectopic thyroid tissue lateral aberrant thyroid thyroid inclusions lymphoepithelial cyst lysosomal storage diseases parasitic nodule parathyroid tissue solid cell nests / ultimobranchial body remnants thymic tissue thyroglossal duct cyst thyroglossal duct carcinoma
Endocrine abnormalities:amiodarone induced hyperthyroidism congenital hypothyroidism hyperthyroidism hypothyroidism
Thyroiditis:acute / infectious thyroiditis autoimmune thyroiditis focal lymphocytic thyroiditis Hashimoto thyroiditis Hashimoto-fibrous lithium thyroiditis palpation thyroiditis postoperative necrotizing granulomas post-partum thyroiditis radiation thyroiditis Riedel thyroiditis SARS related changes silent thyroiditis subacute thyroiditis
Hyperplasia / goiter:amyloid goiter C cell hyperplasia dyshormonogenetic goiter endemic goiter Graves disease multinodular goiter solitary papillary hyperplastic nodule toxic goiter
Other nonneoplastic:black / pigmented thyroid calcification clear cell change crystals Killian-Jamieson diverticulum malakoplakia plasma cell granuloma sarcoidosis teflon
Benign neoplasms:adenolipoma follicular adenoma hyalinizing trabecular tumor lymphangioma paraganglioma postoperative spindle cell nodule rhabdomyoma Rosai-Dorfman disease solitary fibrous tumor solitary thyroid nodule
Thyroid cancer:thyroid cancer-general molecular pathology basics molecular pathology-practical children
Papillary thyroid carcinoma:papillary thyroid carcinoma overview
Main variants:classic cribriform-morular diffuse sclerosing encapsulated microcarcinoma tall cell
Follicular patterned:follicular encapsulated follicular invasive EFVPTC NIFTP diffuse follicular macrofollicular
Rare variants:columnar cell fibromatosis/fasciitis-like hobnail oncocytic solid warthin-like
Other thyroid carcinoma
Main:anaplastic follicular medullary oncocytic (Hürthle cell) tumors poorly differentiated
Rare:CASTLE MASC mixed medullary-follicular tumors mucoepidermoid sclerosing mucoepidermoid carcinoma with eosinophilia secondary tumors / metastases SETTLE squamous cell carcinoma well differentiated WDT-UMP
Other malignancies:angiosarcoma hemangiopericytoma Langerhans cell histiocytosis lymphoma neuroblastoma plasmacytoma sarcoma teratoma
Thyroid stains: AE1/AE3 BCL2 beta-catenin BRAF calcitonin CD5 CD117 CEA chromogranin CK19 Congo Red Galectin3 HBME Ki67 mammaglobin p53 p63 PAS PAX8 PTEN thyroglobulin TTF1

Superpages: entire chapterimagesvirtual slides
Index (Alphabetical table of contents)
A-E:acute / infectious thyroiditis adenolipoma adequacy amiodarone induced hyperthyroidism amyloid goiter anaplastic anatomy angiosarcoma aplasia / hypoplasia atypia of undetermined significance / follicular lesion of undetermined significance autoimmune thyroiditis benign black / pigmented thyroid branchial pouch / cleft anomalies C cell hyperplasia calcification CASTLE children classic clear cell change columnar cell congenital hypothyroidism cribriform-morular crystals diagnostic categories diffuse follicular diffuse sclerosing DiGeorge syndrome dyshormonogenetic goiter ectopic thyroid tissue embryology encapsulated encapsulated follicular endemic goiter
F-N:features to report fibromatosis/fasciitis-like FNA-general focal lymphocytic thyroiditis follicular follicular adenoma follicular neoplasm frozen section Graves disease grossing Hürthle cell neoplasm Hashimoto thyroiditis Hashimoto-fibrous hemangiopericytoma histology hobnail hyalinizing trabecular tumor hyperthyroidism hypothyroidism invasive EFVPTC Killian-Jamieson diverticulum Langerhans cell histiocytosis lateral aberrant thyroid lithium thyroiditis lymphangioma lymphoepithelial cyst lymphoma lysosomal storage diseases macrofollicular malakoplakia malignant MASC medullary microcarcinoma mixed medullary-follicular tumors molecular pathology basics molecular pathology-practical molecular testing in FNA mucoepidermoid multinodular goiter neuroblastoma NIFTP nondiagnostic / unsatisfactory
O-Z:oncocytic oncocytic (Hürthle cell) tumors palpation thyroiditis papillary thyroid carcinoma overview paraganglioma parasitic nodule parathyroid tissue plasma cell granuloma plasmacytoma poorly differentiated post-partum thyroiditis postoperative necrotizing granulomas postoperative spindle cell nodule radiation thyroiditis recommended literature references-additional rhabdomyoma Riedel thyroiditis Rosai-Dorfman disease sarcoidosis sarcoma SARS related changes sclerosing mucoepidermoid carcinoma with eosinophilia secondary tumors / metastases SETTLE silent thyroiditis solid solid cell nests / ultimobranchial body remnants solitary fibrous tumor solitary papillary hyperplastic nodule solitary thyroid nodule squamous cell carcinoma staging subacute thyroiditis suspicious for malignancy tall cell teflon teratoma thymic tissue thyroglossal duct carcinoma thyroglossal duct cyst thyroid cancer-general thyroid inclusions toxic goiter ultrasound warthin-like WDT-UMP well differentiated WHO classification
Thyroid gland books

Adeniran: 2016

Ali: 2017

Boerner: 2016

Braverman: 2020

Duick: 2018

IARC: 2017

Kakudo: 2019

Kini: 2015

Mete: 2016

Nikiforov : 2019

Nose: 2017

Rosai: 2015

Thompson: 2016

Wartofsky: 2016

Wenig: 2015



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