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Skin nonmelanocytic tumor

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Related chapters: Skin melanocytic tumor, Skin nontumor, Soft tissue

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Table of contents
General:books staging-Merkel cell carcinoma staging-nonmelanocytic carcinoma WHO classification
Benign (nonmelanocytic) epidermal tumors or tumor-like lesions:acanthoma fissuratum (pending) benign lichenoid keratosis clear cell acanthoma clear cell papulosis dermatosis papulosa nigra epidermal nevus epidermolytic acanthoma inflammatory linear verrucous epidermal nevus (ILVEN) inverted follicular keratosis large cell acanthoma melanoacanthoma nevus comedonicus (pending) other benign keratoses (pending) porokeratosis pseudoepitheliomatous hyperplasia (pending) seborrheic keratosis warty dyskeratoma
Fibrous, fibrohistiocytic and myofibroblastic neoplasms:acquired digital fibrokeratoma angiofibroma / fibrous papule calcifying aponeurotic fibroma cutaneous fibroepithelial polyps desmoplastic fibroblastoma dermatofibroma (cutaneous fibrous histiocytoma) dermatofibrosarcoma protuberans (DFSP) dermatomyofibroma elastofibroma EWSR1::SMAD3 positive fibroblastic tumor inclusion body fibromatosis Gardner fibroma keloid low grade fibromyxoid sarcoma multinucleate cell angiohistiocytoma myxofibrosarcoma myxoinflammatory fibroblastic sarcoma nuchal type fibroma plaque-like CD34 positive dermal fibroma (pending) pleomorphic fibroma plexiform fibrous histiocytoma sclerotic fibroma superficial angiomyxoma
Cysts:auricular pseudocyst (pending) benign (mature) cystic teratoma cutaneous dental sinus (pending) dermoid cyst digital myxoid cyst endometriosis epidermoid / epidermal inclusion cyst hidrocystoma median raphe cyst (pending) other cysts steatocystoma synovial cysts thyroglossal duct cyst trichilemmal (pilar) type vellus hair cyst
Adnexal tumors
Sweat gland derived (apocrine & eccrine glands):adenocarcinoma of mammary-like glands of vulva adenoid cystic carcinoma (primary cutaneous) apocrine carcinoma (pending) cutaneous adnexal NUT carcinoma cutaneous mixed tumor / chondroid syringoma cylindroma digital papillary adenocarcinoma spiradenoma eccrine syringofibroadenoma endocrine mucin producing sweat gland carcinoma extramammary Paget disease hidradenoma hidradenocarcinoma (pending) hidradenoma papilliferum microcystic adnexal carcinoma myoepithelioma other cutaneous adnexal adenocarcinomas (pending) papillary eccrine adenoma polymorphous sweat gland carcinoma porocarcinoma (pending) poroma primary cutaneous mucinous carcinoma squamoid ductal eccrine carcinoma (pending) syringocystadenoma papilliferum syringoma tubular apocrine adenoma
Follicular derived:basaloid follicular hamartoma cutaneous lymphadenoma dilated pore of Winer (pending) fibrofolliculoma / trichodiscoma hair follicle nevus malignant follicular tumors (pending) pilar sheath acanthoma (pending) pilomatricoma proliferating pilar cyst trichoadenoma (pending) trichilemmoma trichoepithelioma / trichoblastoma trichofolliculoma tumor of the follicular infundibulum
Sebaceous glands:nevus sebaceus of Jadassohn other tumors with sebaceous differentiation (pending) sebaceous hyperplasia sebaceoma sebaceous adenoma sebaceous carcinoma
Premalignant / in situ:actinic keratosis arsenical keratosis bowenoid papulosis extramammary Paget disease HPV associated SIL HPV independent SIL mammary Paget disease penile intraepithelial neoplasia squamous cell carcinoma in situ / Bowen disease
Carcinoma (nonadnexal):approach to cutaneous metastatic disease (pending) basal cell carcinoma cutaneous neuroendocrine carcinoma / Merkel cell carcinoma keratoacanthoma / SCC keratoacanthoma type lymphoepithelioma-like carcinoma metastatic mucoepidermoid carcinoma squamous cell carcinoma verrucous carcinoma
Lymphoma and related disorders (see also Lymphoma chapter):cutaneous lymphoid hyperplasia
Primary cutaneous B cell lymphoma (PCBCL):EBV+ mucocutaneous ulcer intravascular primary cutaneous diffuse large B cell lymphoma, leg type primary cutaneous follicle center lymphoma primary cutaneous marginal zone lymphoma / lymphoproliferative disorder
Cutaneous T cell lymphoma (CTCL):extranodal NK / T cell lymphoma lymphomatoid papulosis mycosis fungoides mycosis fungoides special variants primary cutaneous acral CD8+ primary cutaneous anaplastic large cell lymphoma primary cutaneous CD4+ small / medium primary cutaneous CD8+ aggressive epidermotropic T cell lymphoma primary cutaneous gamma delta primary cutaneous PTCL, NOS Sézary syndrome subcutaneous panniculitis-like systemic EBV+ of childhood
Leukemic infiltrates of skin and cutaneous mastocytosis:blastic plasmacytoid dendritic cell neoplasm cutaneous mastocytosis leukemia cutis myeloid sarcoma
Histiocytoses:ALK+ histiocytosis histiocytoses, overview (pending) juvenile xanthogranuloma Langerhans cell histiocytosis multicentric reticulohistiocytosis necrobiotic xanthogranuloma (pending) other histiocytoses (pending) Rosai-Dorfman disease (RDD)
Vascular tumors:angiokeratoma angiosarcoma atypical vascular lesion post radiation benign lymphangioendothelioma / acquired progressive lymphangioma composite hemangioendothelioma cutaneous epithelioid angiomatous nodule cystic / cavernous lymphangioma epithelioid hemangioendothelioma hemangioendothelioma-kaposiform hemangioendothelioma-retiform intravascular papillary endothelial hyperplasia Kaposi sarcoma lymphangioma / lymphatic malformation papillary intralymphatic angioendothelioma tufted angioma
Hemangioma variants:acquired elastotic hemangioma angiolymphoid hyperplasia with eosinophilia hemangioma & variants glomus tumor lobular capillary hemangioma myopericytoma / myofibroma
Malformations, ectasias and hamartomas of vascular origin:arteriovenous malformation capillary malformations (pending) diffuse dermal angiomatosis eccrine angiomatous hamartoma reactive angioendotheliomatosis (pending) telangiectases (pending) venous lake venous malformations
Neural tumors:dermal nerve sheath myxoma epithelial sheath neuroma granular cell tumor malignant granular cell tumor MPNST neurofibroma palisaded encapsulated neuroma perineurioma plexiform neurofibroma schwannoma
Cutaneous muscle tumors & hamartomas:alveolar rhabdomyosarcoma angioleiomyoma atypical intradermal smooth muscle neoplasm Becker's nevus embryonal rhabdomyosarcoma leiomyoma pleomorphic rhabdomyosarcoma
Nail tumors:normal nail grossing normal nail histology onychocytic carcinoma (pending) onychocytic matricoma (pending) onychomatricoma (pending) onychopapilloma subungual exostosis superficial acral fibromyxoma
Developmental anomalies and other hamartomas:accessory tragus and congenital cartilaginous rest of the neck (pending) connective tissue nevus meningothelial hamartoma of scalp nasal glioma nevus lipomatosus superficialis preauricular sinus / pit (pending) supernumerary digit white sponge nevus
Tumors of uncertain lineage:angiomatoid fibrous histiocytoma atypical fibroxanthoma CRTC1::TRIM11 cutaneous tumor dermal clear cell sarcoma epithelioid fibrous histiocytoma (pending) epithelioid sarcoma cellular neurothekeoma NTRK rearranged spindle cell neoplasm PEComa (pending) pleomorphic dermal sarcoma superficial CD34+ fibroblastic tumor
Stains-Keratinocytic and adnexal neoplasms: adipophilin (sebaceous neoplasms) (pending) AE1 / AE3 BerEP4 (BCC) CD10 (trichoepithelioma versus BCC) CD34 (trichoepithelioma versus BCC) CEA CK5/6 CK7 CK20 EMA PHLDA1 (trichoepithelioma versus BCC) (pending) p40 p63

Stains-Spindle cell neoplasms: AE1 / AE3 ALK CD10 CD31 CD34 CD99 desmin ERG Factor XIIIa SMA vimentin
Melanocytic markers: HMB45 MelanA / MART1 MITF NGFR / p75 (pending) PRAME S100 SOX10

Stains-Specialized markers: BAP1 BRAF MLH1 MLH3 (pending) MSH2 MSH6 PMS2 p16

Superpages: entire chapterimagesvirtual slides
Index (Alphabetical table of contents)
A-E:acanthoma fissuratum (pending) accessory tragus and congenital cartilaginous rest of the neck (pending) acquired digital fibrokeratoma acquired elastotic hemangioma actinic keratosis adenocarcinoma of mammary-like glands of vulva adenoid cystic carcinoma (primary cutaneous) ALK+ histiocytosis alveolar rhabdomyosarcoma angiofibroma / fibrous papule angiokeratoma angioleiomyoma angiolymphoid hyperplasia with eosinophilia angiomatoid fibrous histiocytoma angiosarcoma apocrine carcinoma (pending) approach to cutaneous metastatic disease (pending) arsenical keratosis arteriovenous malformation atypical fibroxanthoma atypical intradermal smooth muscle neoplasm atypical vascular lesion post radiation auricular pseudocyst (pending) basal cell carcinoma basaloid follicular hamartoma Becker's nevus benign (mature) cystic teratoma benign lichenoid keratosis benign lymphangioendothelioma / acquired progressive lymphangioma blastic plasmacytoid dendritic cell neoplasm bowenoid papulosis calcifying aponeurotic fibroma capillary malformations (pending) cellular neurothekeoma clear cell acanthoma clear cell papulosis composite hemangioendothelioma connective tissue nevus CRTC1::TRIM11 cutaneous tumor cutaneous adnexal NUT carcinoma cutaneous dental sinus (pending) cutaneous epithelioid angiomatous nodule cutaneous fibroepithelial polyps cutaneous lymphadenoma cutaneous lymphoid hyperplasia cutaneous mastocytosis cutaneous mixed tumor / chondroid syringoma cutaneous neuroendocrine carcinoma / Merkel cell carcinoma cylindroma cystic / cavernous lymphangioma dermal clear cell sarcoma dermal nerve sheath myxoma dermatofibroma (cutaneous fibrous histiocytoma) dermatofibrosarcoma protuberans (DFSP) dermatomyofibroma dermatosis papulosa nigra dermoid cyst desmoplastic fibroblastoma diffuse dermal angiomatosis digital myxoid cyst digital papillary adenocarcinoma dilated pore of Winer (pending) EBV+ mucocutaneous ulcer eccrine angiomatous hamartoma eccrine syringofibroadenoma elastofibroma embryonal rhabdomyosarcoma endocrine mucin producing sweat gland carcinoma endometriosis epidermal nevus epidermoid / epidermal inclusion cyst epidermolytic acanthoma epithelial sheath neuroma epithelioid fibrous histiocytoma (pending) epithelioid hemangioendothelioma epithelioid sarcoma EWSR1::SMAD3 positive fibroblastic tumor extramammary Paget disease extranodal NK / T cell lymphoma
F-N:fibrofolliculoma / trichodiscoma Gardner fibroma glomus tumor granular cell tumor hair follicle nevus hemangioendothelioma-kaposiform hemangioendothelioma-retiform hemangioma & variants hidradenocarcinoma (pending) hidradenoma hidradenoma papilliferum hidrocystoma histiocytoses, overview (pending) HPV associated SIL HPV independent SIL inclusion body fibromatosis inflammatory linear verrucous epidermal nevus (ILVEN) intravascular intravascular papillary endothelial hyperplasia inverted follicular keratosis juvenile xanthogranuloma Kaposi sarcoma keloid keratoacanthoma / SCC keratoacanthoma type Langerhans cell histiocytosis large cell acanthoma leiomyoma leukemia cutis lobular capillary hemangioma low grade fibromyxoid sarcoma lymphangioma / lymphatic malformation lymphoepithelioma-like carcinoma lymphomatoid papulosis malignant follicular tumors (pending) malignant granular cell tumor mammary Paget disease median raphe cyst (pending) melanoacanthoma meningothelial hamartoma of scalp metastatic microcystic adnexal carcinoma MPNST mucoepidermoid carcinoma multicentric reticulohistiocytosis multinucleate cell angiohistiocytoma mycosis fungoides mycosis fungoides special variants myeloid sarcoma myoepithelioma myopericytoma / myofibroma myxofibrosarcoma myxoinflammatory fibroblastic sarcoma nasal glioma necrobiotic xanthogranuloma (pending) neurofibroma nevus comedonicus (pending) nevus lipomatosus superficialis nevus sebaceus of Jadassohn normal nail grossing normal nail histology NTRK rearranged spindle cell neoplasm nuchal type fibroma
O-Z:onychocytic carcinoma (pending) onychocytic matricoma (pending) onychomatricoma (pending) onychopapilloma other benign keratoses (pending) other cutaneous adnexal adenocarcinomas (pending) other cysts other histiocytoses (pending) other tumors with sebaceous differentiation (pending) palisaded encapsulated neuroma papillary eccrine adenoma papillary intralymphatic angioendothelioma PEComa (pending) penile intraepithelial neoplasia perineurioma pilar sheath acanthoma (pending) pilomatricoma plaque-like CD34 positive dermal fibroma (pending) pleomorphic dermal sarcoma pleomorphic fibroma pleomorphic rhabdomyosarcoma plexiform fibrous histiocytoma plexiform neurofibroma polymorphous sweat gland carcinoma porocarcinoma (pending) porokeratosis poroma preauricular sinus / pit (pending) primary cutaneous acral CD8+ primary cutaneous anaplastic large cell lymphoma primary cutaneous CD4+ small / medium primary cutaneous CD8+ aggressive epidermotropic T cell lymphoma primary cutaneous diffuse large B cell lymphoma, leg type primary cutaneous follicle center lymphoma primary cutaneous gamma delta primary cutaneous marginal zone lymphoma / lymphoproliferative disorder primary cutaneous mucinous carcinoma primary cutaneous PTCL, NOS proliferating pilar cyst pseudoepitheliomatous hyperplasia (pending) reactive angioendotheliomatosis (pending) Rosai-Dorfman disease (RDD) Sézary syndrome schwannoma sclerotic fibroma sebaceoma sebaceous adenoma sebaceous carcinoma sebaceous hyperplasia seborrheic keratosis spiradenoma squamoid ductal eccrine carcinoma (pending) squamous cell carcinoma squamous cell carcinoma in situ / Bowen disease staging-Merkel cell carcinoma staging-nonmelanocytic carcinoma steatocystoma subcutaneous panniculitis-like subungual exostosis superficial acral fibromyxoma superficial angiomyxoma superficial CD34+ fibroblastic tumor supernumerary digit synovial cysts syringocystadenoma papilliferum syringoma systemic EBV+ of childhood telangiectases (pending) thyroglossal duct cyst trichilemmal (pilar) type trichilemmoma trichoadenoma (pending) trichoepithelioma / trichoblastoma trichofolliculoma tubular apocrine adenoma tufted angioma tumor of the follicular infundibulum vellus hair cyst venous lake venous malformations verrucous carcinoma warty dyskeratoma white sponge nevus WHO classification
Skin nonmelanocytic tumor books

Bhawan: 2022

Biswas: 2017

Bolognia: 2024

Brenn: 2021

Busam: 2015

Calonje: 2019

Carter: 2015

Cerroni: 2020

Dadzie: 2016

Elder: 2020

Elder: 2022

Elston: 2018

Gardner: 2019

Gru: 2023

IARC: 2018

Johnston: 2023

Patterson: 2020

Plaza: 2016

Rapini: 2021

Subtil: 2019

Tetzlaff: 2021



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