Breast-nonmalignant

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Breast-nonmalignant

Parasites

Myiasis

Reviewer: Hind Nassar, M.D. in January 2009 (see Authors page)

Revised: 1 October 2012, last major updated March 2010

Definition

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● Infestation of body by larva of Diptera (flies with 2 wings)

● Larvae usually occupy skin and subcutis, but potentially any organ

Terminology

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Epidemiology

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● Dermatobia hominis (human botfly) is obligate Diptera that needs to feed on a host to complete its development

● Indigenous to Central and South America, occasionally reported in USA (Radiology 2001;218:517)

● Cordylobia anthropophaga (Tumbu fly) is endemic in Nigeria (BMC Surg 2004;4:5)

Etiology

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Clinical features

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● Cause abscess and rarely granulomatous response to dead larvae

● Often multiple infestations in breast

● Also affects lips of breast fed infants (Int J Dermatol 2006;45:1069)

Prognostic factors

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Case reports

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● 54 year old woman with breast mass due to chronic granulomatous response to botfly (Archives 1999;123:829)

Treatment

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Clinical images

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Breast infested by Extracted Tumbu fly larvae Human botfly larvae

Tumbu fly larvae extracted from a dog

Gross description (Macroscopy)

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Gross images

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Micro description (Histopathology)

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● Chronic granulomatous response, dead larvae

Micro images

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Botfly - respiratory spiracles Granulomatous response around a spine

Drawings

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Virtual Slides

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Videos

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Cytology description

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Cytology images

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Positive stains

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Negative stains

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Electron microscopy descriptions

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Electron microscopy images

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Molecular / cytogenetics description

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Molecular / cytogenetics images

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Differential Diagnosis

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● Ticks: have legs and mouth and don’t burrow deeply into skin

● Tunga penetrans: flea with legs, almost always involves feet, has cuticle > 20 microns, lacks a spine

Additional references

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End of Breast-nonmalignant > Parasites > Myiasis

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