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CD Markers
CD31

Reviewer: Lauren N. Stuart, M.D., M.B.A. (see Reviewers page)
Revised: 8 May 2013, last major update May 2013
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.

General
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Terminology
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Physiology
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Clinical features
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Interpretation
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Uses
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Micro images
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Normal structures:

Glomeruli-A

Alveoli-A

Spleen-A

Liver-2A


Liver-A

Lymph nodes-A

Skin-A

Brown fat: normal and hibernoma



Benign vascular tumors / processes:

Breast-pseudoangiomatous
hyperplasia (clefts CD31-)

Kidney-glomus tumor

Lung-lymphangiomatosis

Lymphangioma-3


Skin-diffuse dermal angiomatosis

Skin-epithelioid hemangioma

Skin: hobnail hemangioma

Spleen-sclerosing angiomatoid
nodular transformation



Malignant vascular tumors other than angiosarcoma:

CNS hemangiopericytoma is CD34+ (left), CD31- (right)

Epithelioid hemangioendothelioma


Kaposi sarcoma

Kaposi sarcoma

Retiform hemangioendothelioma



Angiosarcoma:

Breast

Heart

Liver-4

Lung-4


Paratesticular

Skin-3A

Small intestine-6

Unspecified-E/F


Epithelioid angiosarcoma - lower leg

Epithelioid angiosarcoma-1A

Epithelioid angiosarcoma-5

Epithelioid angiosarcoma-4



Lymphovascular invasion:

Breast

Breast-microvessel density

Colorectal carcinoma

Lymph node vessels and sinuses


Oral cavity squamous cell carcinoma

Uterus: endometrial carcinoma-stage I

Uterine leiomyosarcoma



Other tumors:

Langerhans cells

Pancreatic endocrine neoplasm


Positive stains - normal
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Positive stains - disease
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Negative stains
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End of CD Markers > CD31


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