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Coagulation

Coagulation laboratory tests

Clot retraction


Reviewer: Jeremy Parsons, M.D. (see Reviewers page)
Revised: 20 June 2012, last major update June 2012
Copyright: (c) 2002-2012, PathologyOutlines.com, Inc.

General
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● Obsolete test
● Evaluates how well platelets keep the clot adhered to the sides of specimen tube
● Uses whole blood in red top tube
● Examine clot at 1, 2, 4 and 24 hours for clot retraction
● After clot forms, remaining 40-60% consists of serum and red blood cell “fall-out” from clot
● Must have normal fibrinogen and hematocrit for test be accurate

Reduced clot formation:
● Glanzmann thrombasthenia: reduced glycoprotein IIb/IIIa causes reduced platelet aggregation and clot retraction
● DIC, hypofibrinogenemia, dysfibrinogenemia (small clot with increased red blood cell “fall-out”)

End of Coagulation > Coagulation laboratory tests > Clot retraction


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