Emphysematous cholecystitis

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 5 October 2018, last major update September 2012

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Emphysematous cholecystitis gallbladder

Cite this page: Gulwani, H. Emphysematous cholecystitis. website. Accessed November 17th, 2018.
Definition / general
  • Rare form of acute cholecystitis with gas in gallbladder wall, associated with diabetes and peripheral atherosclerotic disease
  • 2/3 men, usually 50 - 70 years old, diagnosed with ultrasonographic studies
  • May be due to vascular compromise of cystic artery
  • Associated with acalculous disease, gallbladder perforation, Clostridium welchii and E. coli infection
Gross images

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Transmural infarction and hemorrhagic necrosis

Perforation within
a large area of

Microscopic (histologic) images

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Multiple areas of gas (long arrows) in wall