Placental gross/microscopic abnormalities, non-neoplastic
Placental edema (placental hydrops)
Reviewers: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 16 November 2011, last major update October 2011
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● Accumulation of fluid in the placenta and umbilical cord
● Results from a variety of fetal or maternal factors including erythroblastosis fetalis, hemolytic disease of the newborn, infection, cardiac anomalies, fetal anemia, hemorrhage, congenital anomalies, chromosomal disorders or tumors
● Placenta is enlarged and pale when edema is marked
● Placental weight may be greater than expected for gestational age
● Enlarged villi with edematous stroma and increased numbers of Hofbauer cells (macrophages)
● Underlying cause of edema may be diagnosed based on other histologic findings
End of Placenta > Placental gross/microscopic abnormalities, non-neoplastic > Placental edema (placental hydrops)
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