Home   Chapter Home   Jobs   Conferences   Fellowships   Books



Advertisement

Small bowel (small intestine)

Benign tumors and tumor-like conditions

Pneumatosis cystoides intestinalis


Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 22 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
=========================================================================

● Submucosal gas-filled cysts in GI tract
● Called mucosal pseudolipomatosis if it resembles lipomatosis

Clinical features
=========================================================================

● Part of differential diagnosis of acute abdomen (World J Gastroenterol 2012;18:453)
● In infants, associated with necrotizing enterocolitis and may be fatal; also associated with cystic fibrosis, congenital heart defects
● In adults, either idiopathic or varied clinical settings including chemotherapy, chronic lung disease, drugs, ischemic colitis, obstruction, scleroderma (World J Gastroenterol 2011;17:4932, Arch Pathol Lab Med 2010;134:378)
● Often indolent clinical course, although radiographically resembles carcinoma
● Considered a finding, not a diagnosis

Case reports
=========================================================================

● 6 year old girl with ulcerative colitis (Arch Pathol Lab Med 1999;123:354)
● 73 year old woman with dysplasia in perforated intestinal pneumatosis (World J Gastroenterol 2009;15:4189)
● Idiopathic myointimal hyperplasia of mesenteric veins and pneumatosis intestinalis (J Crohns Colitis 2011;5:239)

Gross description
=========================================================================

● Polypoid grapelike masses protrude through mucosa
● Soft, bluish, and often sessile,‘‘bubble wrap’’ crackling noise while handling the specimen

Clinical images
=========================================================================



Endoscopy

Gross images
=========================================================================



Various images

Micro description
=========================================================================

● Submucosal cysts lined by multinucleated giant cells
● Mucosa contains cryptitis, crypt abscesses, granulomas
● May also resemble lipomatosis

Micro images
=========================================================================



Various images

Differential diagnosis
=========================================================================

Crohn’s disease

End of Small bowel (small intestine) > Benign tumors and tumor-like conditions > Pneumatosis cystoides intestinalis


This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).