Stains
NapsinA

Author: Nat Pernick, M.D. (see Authors page)

Revised: 16 November 2015, last major update June 2012

Copyright: (c) 2002-2015, PathologyOutlines.com, Inc.

PubMed Search: Napsin A

Definition / General
  • A novel aspartic proteinase of the pepsin family involved in the maturation of surfactant protein B
  • Found primarily in lung and kidney
  • Lack of NapsinA expression in tumor cells may be poor prognostic marker in pulmonary adenocarcinoma (Lung Cancer 2012;77:156)
Uses by Pathologists
Micro Images

Images hosted on Other servers:

Missing Image

Lung adenocarcinoma, compared w/ TTF1

Missing Image Missing Image Missing Image Missing Image

Lung adenocarcinoma

Missing Image

Cerebellar tumor specimen

Missing Image

Lung squamous cell carcinoma

Missing Image Missing Image

Various images



Nature images:

Missing Image

Kidney, normal, renal cell carcinoma

Missing Image

Lung, epithelium is NapsinA+

Missing Image

Lung adenocarcinoma



Cytology Images
Missing Image

Pulmonary ADC

Missing Image

Pulmonary SCC

Missing Image

SCC

Missing Image

ADC

Missing Image Missing Image Missing Image

PDC

Positive Staining - Normal
Positive Staining - Disease
Electron Microscopy Images
Missing Image

Type II pneumocytes