Author: Nat Pernick, M.D. (see Authors page)

Revised: 11 December 2015, last major update February 2014

Copyright: (c) 2014-2015,, Inc.

PubMed Search: SOX10[title]

Cite this page: SOX10. website. Accessed April 24th, 2017.
Definition / General
  • SRY-related HMG-box 10 (SOX10) protein
  • Transcription factor known to be crucial in the specification of the neural crest and maintenance of Schwann cells and melanocytes
  • Expressed in nuclei of melanocytes, breast myoepithelial cells
Clinical Features
Uses by Pathologists
Micro Images

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Melanoma (fig b, f)

Negative Staining