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Trachea

Infectious disorders

Diphtheria

Reviewer: Adriana Handra-Luca, M.D. (see Reviewers page)
Revised: 8 February 2013, last major update October 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
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● Tracheal involvement in pharyngeal/laryngeal diphtheria is uncommon
● Late appearance of grey-brown thick and firm false membranes of pharynx and larynx
● Death occurs rarely in non-immunized children (Vestn Otorinolaringol 1995;(2):31)

Case reports
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● Fatal case in a nonimmunized child (Pediatr Pathol 1994;14:391)

Gross images
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6 year old child's trachea and major bronchi with mucosa damaged by toxin produced by Corynebacterium diphtheriae

Micro images
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Complete necrosis of surface epithelium, which has been replaced by pseudomembrane of fibrin, necrotic cells and bacteria

Virtual slides
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Diphtheria

End of Trachea > Infectious disorders > Diphtheria

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