Cervix
Mesenchymal / mixed epithelial & mesenchymal tumors
Leiomyoma
Authors: Farnaz Hasteh, M.D., Branko Perunovic, D.M.
Topic Completed: 1 May 2007
Minor changes: 17 November 2020
Copyright: 2007-2021, PathologyOutlines.com, Inc.
PubMed Search: Leiomyoma[title] cervix
Table of Contents
Definition / general | Case reports | Gross description | Microscopic (histologic) description | Microscopic (histologic) images | Cytology description | Cytology imagesCite this page: Hasteh F, Perunovic B. Leiomyoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cervixleiomyoma.html. Accessed January 22nd, 2021.
Definition / general
- Uncommon; only 8% of uterine leiomyomas occur in cervix
- Clinically may mimic an endocervical polyp
- Unusual finding in a pap smear, even if present in cervix
Case reports
- 54 year old woman with pedunculated leiomyoma (Gynecol Oncol 2005;97:253)
- Patient with large leiomyoma causing heavy hemorrhage (Clin Exp Obstet Gynecol 2003;30:144)
- Patient with benign cervical leiomyoma (Gynecol Oncol 1996;62:119)
Gross description
- Firm, whorled cut surface similar to uterine leiomyoma
- Usually 1 cm or less
Microscopic (histologic) description
- Resembles uterine leiomyoma
- Often prominent thick walled blood vessels
- May have mitotic figures below ulcerated areas
Microscopic (histologic) images
AFIP images
Spindled cells in streaming pattern
Cytology description
- Not identified in Pap smear unless a cervical leiomyoma is present which ulcerates (DeMay: The Pap Test: Exfoliative Gynecologic Cytology; 2005)
- Pap smear diagnosis is usually infectious or otherwise abnormal (J Med Assoc Thai 1991;74:471)
- Spindle cells with cigar shaped nuclei, bland chromatin
- Nuclear degeneration can occur
Cytology images
Images hosted on other servers:
Esophageal leiomyoma showing groups of spindled cells with relatively low cellularity
