Colon non tumor
Infectious colitis (specific microorganisms)
Basidiobolomycosis

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 4 January 2017, last major update May 2013

Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.

PubMed Search: basidiobolomycosis
Cite this page: Basidiobolomycosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colonbasidio.html. Accessed January 16th, 2017.
Definition / General
Sites
  • More common in skin and subcutis, rare in GI tract
Case Reports
Treatment
  • Both surgical and medical; patients should undergo resection of all affected bowel segments and debridement of involved tissue followed by antifungal therapy (prolonged treatment with itraconazole) (Arch Pathol Lab Med 2009;133:1938)
Gross Images

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Adherent small bowel loop

Postmortem liver

Micro Description
  • Marked mural thickening with fibrosis, prominent eosinophils, palisading granulomas around pale thin-walled but broad and often aseptate hyphae
  • Also spore-like spherules with occasional septal hyphae surrounded by a thick eosinophilic cuff (Splendore-Hoeppli phenomenon)
Micro Images

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Acute / chronic inflammation

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Splendore-Hoeppli phenomenon

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Zygospore

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Periodic acid-Schiff stain


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Fungal hyphae-1

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Fungal hyphae-2

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Liver biopsy

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Spore forms

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Various images