Nonneoplastic disease

Author: Vijay Shankar, M.D. (see Authors page)

Revised: 22 August 2017, last major update January 2013

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Ganglion [title] joints

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Cite this page: Shankar, V. Ganglion. website. Accessed January 19th, 2019.
Definition / general
  • Common tumor-like lesion arising from soft tissue, caused by mucoid degeneration of joint capsule, tendon or tendon sheath
  • Small cyst-like mass (no epithelial lining) near joint capsule or tendon sheath
  • Common site is wrist, also hand and foot, rarely in intratendinous region
  • May cause pain, weakness, bone changes, partial disability of joint
  • May be due to injury or overuse of joint
  • May be multilocular
  • Fluid is similar to synovial fluid
Case reports
Clinical images

Images hosted on other servers:

Various images

Gross description
  • Usually does not communicate with joint space; rarely is intraosseus (medial malleolus of tibia)
Microscopic (histologic) description
  • Dense fibrous tissue, with no synovial or epithelial lining; inflammation may be associated with cyst rupture
Microscopic (histologic) images

Images hosted on other servers:

Cystic space lined by histiocytes
and granulation tissue with
moderate acute and chronic
inflammation of cyst wall