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Joints
Joint tumors
Synovial lipomatosis
Reviewer: Vijay Shankar, M.D. (see Reviewers page)
Revised: 15 June 2013, last major update June 2013
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
General
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- Also called Hoffa's disease, villous lipomatous proliferation of synovium, lipoma arborescens
- Pseudotumor of synovium with distinct histomorphology, possibly due to inappropriate fat deposition and degenerative articular diseases of joints (J Lab Physicians 2011;3:84)
Clinical features
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- Rare; usually knee but may occur in any joint
- Unknown etiology
- Males commonly affected with pain and swelling of joint
Treatment
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Gross description
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- Enlargement of infrapatellar fat pad with pain in anterior compartment of knee; synovium is papillary, yellow and fatty
Micro description
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- Synovial hyperplasia with unremarkable fat extending to synovial lining; occasional chronic inflammatory infiltrate
Micro images
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Villi-like structures
Papillary architecture
Mature adipocytes
Focal hyperplasia
Few mature lipocytes
End of Joints > Joint tumors > Synovial lipomatosis
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