Nasal cavity, paranasal sinuses, nasopharynx
Inflammatory / infectious lesions
• Bacterial / fungal / viral
Invasive fungal sinusitis

Topic Completed: 1 November 2004

Minor changes: 2 March 2020

Copyright: 2004-2020,, Inc.

PubMed Search: Invasive fungal sinusitis nasal

Nat Pernick, M.D.
Page views in 2019: 3,223
Page views in 2020 to date: 1,058
Cite this page: Pernick N. Invasive fungal sinusitis. website. Accessed July 13th, 2020.
Definition / general
  • Relatively common life threatening fungal infection, associated with diabetic ketoacidosis, poor glycemic control or immunosuppression
  • Spreads rapidly across nerves and tissue planes to blood vessels of orbit and brain, causes thrombosis, hemorrhage and infarction
  • Member of phylum Zygomycota, class Zygomycetes, order Mucorales; found in high organic matter and soil
  • Mortality rate of 48%
Case reports
Microscopic (histologic) description
  • Broad nonseptate hyphae branching at 90 degrees, accompanied by numerous neutrophils and histiocytes within granulation tissue
Microscopic (histologic) images

Images hosted on other servers:

Fungal hyphae in vessel lumen that infiltrate vessel wall

Asexual structures (very rare in tissue)

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