Nasal cavity, paranasal sinuses, nasopharynx
Bacterial / fungal / viral
Invasive fungal sinusitis

Topic Completed: 1 November 2004

Revised: 21 August 2019

Copyright: 2004-2019,, Inc.

PubMed Search: Invasive fungal sinusitis nasal

Nat Pernick, M.D.
Page views in 2018: 2,699
Page views in 2019 to date: 2,683
Cite this page: Pernick N. Invasive fungal sinusitis. website. Accessed October 21st, 2019.
Definition / general
  • Relatively common life threatening fungal infection, associated with diabetic ketoacidosis, poor glycemic control or immunosuppression
  • Spreads rapidly across nerves and tissue planes to blood vessels of orbit and brain, causes thrombosis, hemorrhage and infarction
  • Member of phylum Zygomycota, class Zygomycetes, order Mucorales; found in high organic matter and soil
  • Mortality rate of 48%
Case reports
Microscopic (histologic) description
  • Broad nonseptate hyphae branching at 90 degrees, accompanied by numerous neutrophils and histiocytes within granulation tissue
Microscopic (histologic) images

Images hosted on other servers:

Fungal hyphae in vessel lumen that infiltrate vessel wall

Asexual structures (very rare in tissue)

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