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Penis and scrotum
Inflammatory lesions
Mucoid cyst
Reviewers: Antonio Cubilla, M.D. and Alcides Chaux, M.D. (see Author/Reviewers page)
Revised: 20 February 2010, last major update February 2010
Copyright: (c) 2002-2010, PathologyOutlines.com, Inc.
Definition
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● Inflammatory lesion due to accessory urethral canals (entrapped urothelium during development) on foreskin or glans, with intraepithelial mucous cells or glands
Terminology
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● Also includes some median raphe cysts (uncommon; found from distal penis and scrotum toward the perineum in a midline position; considered a congenital alteration in embryologic development, Urology 2008;71:830)
Clinical features
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● Slow growing painless cystic mass
● Often has an incorrect clinical and pathologic diagnosis (J Urol 1976;115:397)
Case reports
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● 43 year old man with mucinous median raphe cyst of glans penis (Dermatol Online J 2005;11:37)
Treatment
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● Excision is curative
Clinical images
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Median raphe cysts
Micro description (Histopathology)
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● Epithelium is stratified columnar with intraepithelial mucous cells or associated mucous glands
Micro images
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Cystic cavity lined by Note single larger mucinous cell within the
pseudostratified columnar epithelium epithelium and hints of decapitation
secretion in the apical border of luminal cells
CK7 CK13 CEA
Positive stains
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● CK7, CK13, CEA
Negative stains
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● CK20
End of Penis and scrotum > Inflammatory Lesions > Mucoid cyst
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