Placental gross / microscopic abnormalities, nonneoplastic
Amnion nodosum

Author: Mandolin Ziadie, M.D. (see Authors page)

Revised: 12 October 2017, last major update September 2011

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Amnion nodosum

Cite this page: Ziadie, M. Amnion nodosum. website. Accessed November 15th, 2018.
Definition / general
  • Small deposits on fetal surface
  • Seen in placentas affected by oligohydramnios, which may be associated with fetal renal agenesis and pulmonary hypoplasia
  • May be due to desquamated skin or membrane injury
Gross description
  • Multiple yellow tan superficial amniotic lesions, 0.2 to 0.4 cm and usually near insertion of umbilical cord
Microscopic (histologic) description
  • Nodules of protuberant eosinophilic fibrinous material with entrapped squamous cells
  • Associated with stratified squamous metaplasia
Microscopic (histologic) images

Images hosted on other servers:

Various images