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Placenta

Placental gross/microscopic abnormalities, non-neoplastic

Low weight / small for gestational age


Reviewers: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 15 November 2011, last major update October 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.

Definition
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● Placental weight that falls below the 10th percentile for gestational age

Etiology
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● Due to a variety of causes including fetal factors (prematurity, fetal malformations or trisomy, small for date fetus, neonatal high hemoglobin or lower than expected body size in later childhood for fetus) and maternal factors (low pregnancy weight gain, low maternal pregravid body weight, high maternal hemoglobin during pregnancy, gestational hypertension, paid employment during pregnancy, low parity, maternal diabetes, CMV, HSV or other chronic infections; other causes of reduced uteroplacental blood flow)

Micro description
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● Evidence of placental hypoxia including terminal villous hypoplasia, chorangiosis or Tenney-Parker change

End of Placenta > Placental gross/microscopic abnormalities, non-neoplastic > Low weight / small for gestational age


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