Placental gross/microscopic abnormalities, non-neoplastic
Maternal floor infarction
Reviewers: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 15 November 2011, last major update October 2011
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● Massive deposition of intervillous fibrin that entrap the villi of the basal plate, extending to a thickness of at least 3mm
● May be accompanied by massive perivillous fibrin deposition
● Associated with recurrent abortions / stillbirth, fetal growth restriction or neurologic impairment
● Seen in 0.09–0.5% of placentas
● May be due to ischemic / infectious damage to deciduas basalis, including low maternal blood volume
● Associated with acute chorioamnionitis (Hum Pathol 1985;16:823)
● Diffusely thick, stiff and pale basal plate
● Thick (>0.3 cm) bands of fibrin with intermingled trophoblast cells involve the entire basal plate and may extend up into the intervillous space
End of Placenta > Placental gross/microscopic abnormalities, non-neoplastic > Maternal floor infarction
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