Placenta
Placental gross / microscopic abnormalities, nonneoplastic
Maternal floor infarction


Topic Completed: 1 October 2011

Revised: 18 February 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Maternal floor infarction

Mandolin S. Ziadie, M.D.
Page views in 2018: 1,514
Page views in 2019 to date: 1,040
Cite this page: Ziadie MS. Maternal floor infarction. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/placentamatfloorinfarct.html. Accessed September 17th, 2019.
Definition / general
  • Massive deposition of intervillous fibrin that entrap the villi of the basal plate, extending to a thickness of at least 3 mm
  • May be accompanied by massive perivillous fibrin deposition
  • Associated with recurrent abortions / stillbirth, fetal growth restriction or neurologic impairment
  • Seen in 0.09 - 0.5% of placentas
Etiology
  • May be due to ischemic / infectious damage to deciduas basalis, including low maternal blood volume
  • Associated with acute chorioamnionitis (Hum Pathol 1985;16:823)
Gross description
  • Diffusely thick, stiff and pale basal plate
Microscopic (histologic) description
  • Thick ( > 0.3 cm) bands of fibrin with intermingled trophoblast cells involve the entire basal plate and may extend up into the intervillous space
Back to top