Nonneoplastic placental conditions and abnormalities


Maternal floor infarction

Last author update: 1 October 2011
Last staff update: 29 October 2020

Copyright: 2002-2023,, Inc.

PubMed Search: Maternal floor infarction

Mandolin S. Ziadie, M.D.
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Cite this page: Ziadie MS. Maternal floor infarction. website. Accessed June 1st, 2023.
Definition / general
  • Massive deposition of intervillous fibrin that entrap the villi of the basal plate, extending to a thickness of at least 3 mm
  • May be accompanied by massive perivillous fibrin deposition
  • Associated with recurrent abortions / stillbirth, fetal growth restriction or neurologic impairment
  • Seen in 0.09 - 0.5% of placentas
  • May be due to ischemic / infectious damage to deciduas basalis, including low maternal blood volume
  • Associated with acute chorioamnionitis (Hum Pathol 1985;16:823)
Gross description
  • Diffusely thick, stiff and pale basal plate
Microscopic (histologic) description
  • Thick ( > 0.3 cm) bands of fibrin with intermingled trophoblast cells involve the entire basal plate and may extend up into the intervillous space
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