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Placenta

Placental gross/microscopic abnormalities, non-neoplastic

Placental site subinvolution


Reviewer: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 23 November 2011, last major update November 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.

Definition
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● Delayed / incomplete sloughing of the modified spiral arteries in the superficial myometrium beneath the placental attachment site
● Important cause of late postpartum bleeding

Etiology
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● May be due to deficiency in immunologic factors necessary for normal involution of uteroplacental arteries

Micro description
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● Curettings show large, dilated vessels that lack a medial coat and are partially / completely thrombosed
● Trophoblasts may be present

End of Placenta > Placental gross/microscopic abnormalities, non-neoplastic > Placental site subinvolution


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