Placental gross/microscopic abnormalities, non-neoplastic
Placental site subinvolution
Reviewer: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 23 November 2011, last major update November 2011
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● Delayed / incomplete sloughing of the modified spiral arteries in the superficial myometrium beneath the placental attachment site
● Important cause of late postpartum bleeding
● May be due to deficiency in immunologic factors necessary for normal involution of uteroplacental arteries
● Curettings show large, dilated vessels that lack a medial coat and are partially / completely thrombosed
● Trophoblasts may be present
End of Placenta > Placental gross/microscopic abnormalities, non-neoplastic > Placental site subinvolution
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