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Placenta

Placental gross/microscopic abnormalities, non-neoplastic

Distal villous hyperplasia (villous dysmaturity / delayed villous maturation)


Reviewers: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 17 November 2011, last major update October 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.

Definition
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● Abnormal villous maturation associated with diabetes
● Neonatal hepatitis should be suspected if pigment-laden Hofbauer cells are present

Gross description
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● Placenta is usually large for gestational age

Micro description
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● Terminal villi may be hypervascular and edematous with reduced numbers of syncytial knots
● Trophoblast lacks normal syncytiotrophoblast

End of Placenta > Placental gross/microscopic abnormalities, non-neoplastic > Distal villous hyperplasia (villous dysmaturity / delayed villous maturation)


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