Prostate
Miscellaneous
Grossing prostate specimens

Authors: Komal Arora, M.D. (see Authors page)

Revised: 8 September 2016, last major update June 2012

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed search: grossing prostatic specimens

Cite this page: Grossing prostate specimens. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/prostategrossing.html. Accessed December 7th, 2016.
Definition / General
Needle core biopsies:

Radical prostatectomy:

Systemic sampling (12-13 blocks):
  • Ink surface with 2 colors to designate left versus right
  • Amputate apex and serial section parallel to urethra
  • For base, thin shave or amputate and serial section parallel to urethra
  • Submit base of seminal vesicles, margins of right and left vas deferens
  • Serial section prostate perpendicular to urethra, submit all gross tumor (look in peripheral zone, posterior or posterior-lateral area for asymmetry in size, color, density between left and right sides)
  • Special device may assist in generating sections of uniform thickness (J Magn Reson Imaging 2010;32:992)


Transurethral resection biopsies (prostate chips):
  • If specimen 12 g or less, submit all
  • If specimen more than 12g, submit at least 12 g
  • If unsuspected carcinoma found that involves 5% or less of tissue examined, submit remaining tissue (may increase stage from T1a to T1b)
  • Reference: Arch Pathol Lab Med 2006;130:936
Diagrams / Tables
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Excision can cause increase in apparent tumor stage

Gross Images
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Device to generate uniform thickness of sections in radical prostatectomy



Whole mount sectioning