Prostate gland & seminal vesicles



Topic Completed: 1 June 2012

Minor changes: 29 October 2020

Copyright: 2003-2021,, Inc.

PubMed search: grossing prostatic specimens

Komal Arora, M.D.
Page views in 2020: 2,038
Page views in 2021 to date: 1,690
Cite this page: Arora K. Grossing. website. Accessed December 7th, 2021.
Definition / general
Needle core biopsies:

Radical prostatectomy:

Systemic sampling (12-13 blocks):
  • Ink surface with 2 colors to designate left versus right
  • Amputate apex and serial section parallel to urethra
  • For base, thin shave or amputate and serial section parallel to urethra
  • Submit base of seminal vesicles, margins of right and left vas deferens
  • Serial section prostate perpendicular to urethra, submit all gross tumor (look in peripheral zone, posterior or posterior-lateral area for asymmetry in size, color, density between left and right sides)
  • Special device may assist in generating sections of uniform thickness (J Magn Reson Imaging 2010;32:992)

Transurethral resection biopsies (prostate chips):
  • If specimen 12 g or less, submit all
  • If specimen more than 12g, submit at least 12 g
  • If unsuspected carcinoma found that involves 5% or less of tissue examined, submit remaining tissue (may increase stage from T1a to T1b)
  • Reference: Arch Pathol Lab Med 2006;130:936
Gross images

Images hosted on other servers:

Device to generate uniform thickness of sections in radical prostatectomy

Whole mount sectioning

Back to top
Image 01 Image 02