Skin inflammatory (nontumor)
Infectious disorders
Cysticercosis


Topic Completed: 1 January 2016

Revised: 1 April 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Cysticercosis [title] skin

Abha Soni, D.O., M.P.H.
Page views in 2018: 6,601
Page views in 2019 to date: 6,268
Cite this page: Soni A Cysticercosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skinnontumorcysticercosis.html. Accessed October 22nd, 2019.
Definition / general
  • Tissue infection caused by ingestion of larval cysts of the cestode Taenia solium (cysticercus cellulose) (CDC: Cysticercosis [Accessed 27 August 2018])
  • Acquired by swallowing food, water or feces contaminated by T. solium eggs
  • In cystecicercosis, the human represents an intermediate host, and the parasite develops cysticerci in various organs

  • Taeniasis: infection caused by the adult tapeworm in the human intestine, which occurs from ingestion of larvae in undercooked pork
  • Cysticerci: larval forms of tapeworms found within a fluid filled cyst
Epidemiology
  • 50 - 100 million people infected worldwide (eMedicine: Cysticercosis [Accessed 27 August 2018])

  • Endemic areas include: Central and South America, India, China Southeast Asia, Africa and Eastern Europe

  • In the United States, infection is most common in rural areas and among Latin American immigrants
Sites
  • Cysticerci develop in the nervous system, heart, skeletal muscle, eyes and subcutaneous tissue
Diagrams / tables

Images hosted on other servers:
Missing Image

Life cycle

Etiology
  • Accidental ingestion of eggs or gravid proglottids of Taenia solium by human host via infected food, water or feces
Clinical features
  • Cysticercosis of the skin is rare
  • It presents as a palpable, subcutaneous nodule
Diagnosis
  • Thorough history, skin biopsy, serology (serum or CSF) and imaging can aid in the proper diagnosis
Radiology description
  • CT scan can reveal hyperdense lesions in subcutaneous tissue with or without calcification
  • Ultrasound can reveal cystic lesions
Radiology images

Images hosted on other servers:
Missing Image

Computed tomography

Case reports
Treatment
  • Praziquantel and albendazole are effective
  • Surgery is appropriate for large, solitary lesions which would otherwise require prolonged antiparasitic therapy
Clinical images

Images hosted on other servers:
Missing Image

Gigantic cysticercosis pseudo tumour

Missing Image

Swelling over neck

Missing Image

Swellings over back

Gross description
  • Circumscribed, white to tan, cystic nodules containing a clear fluid
  • Cyst sizes vary, but commonly 1mm - 2cm
  • Larval forms identified within the cyst cavity
Gross images

Images hosted on other servers:
Missing Image

Cysticercosis pseudotumor

Missing Image

Well circumscribed nodule

Missing Image

Specimen from trunk

Microscopic (histologic) description
  • The cystic cavity contains the the larval form: scolex with hooklets and two pairs of suckers
  • The larval form, composed of duct-like invaginations, is lined by a double layered, eosinophilic membrane
  • Its body wall exhibits a myxoid matrix and calcareous bodies (calcified concretions)
  • Birefringent hooklets may be identified
  • Variable granulomatous reaction, inflammatory infiltrate with lymphocytes and eosinophils, fibrosis and calcification
Microscopic (histologic) images
Contributed by Dr. Faheema Hasan, Moti Lal Nehru Medical College (India) for Case of the Week #458:


Images hosted on other servers:
Missing Image

Fibrosis and inflammation

Missing Image

Hooklet of cysticercus

Missing Image

Parasitic granuloma



Contributed by Dr. Thiriveni Balajji and Dr. M. Kavitha, Coimbatore Medical College (India):
Missing Image Missing Image Missing Image

Various images

Cytology description
  • Fibrillary stroma with interspersed nuclei and a honeycomb pattern
  • Mixed inflammatory infiltrate
Back to top