Skin inflammatory (nontumor)
Panniculitis
Weber-Christian disease


Topic Completed: 1 August 2011

Revised: 2 April 2019

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PubMed Search: Weber-Christian disease
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Cite this page: Hamodat M Weber-Christian disease. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skinnontumorweberchristian.html. Accessed June 15th, 2019.
Definition / general
  • Also called relapsing febrile nodular panniculitis
  • Recurring tender erythematous subcutaneous nodules of legs and trunk, usually in women, with malaise and fever
  • Some cases are associated with other disorders
  • No known risk factors
Epidemiology
  • Females 30 - 60 years of age, although can occur in both sexes, in all ages, and rarely in infants
Microscopic (histologic) description
  • Lobular acute and subacute inflammation of subcutis with fat cell necrosis; later fibrosis and macrophages
Differential diagnosis
Additional references
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