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Cite this page: Iron. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsiron.html. Accessed July 12th, 2017.
Definition / general
- Also called hemosiderin (storage iron granules)
- See also Hales colloidal iron
- Perl’s method (Prussian blue stain): hydrochloric acid releases the protein bound to ferric iron, then potassium ferrocyanide binds with ferric iron to form ferric ferrocyanide, an insoluble blue compound
- Hemosiderin may be present in areas of old hemorrhage or be deposited in tissues with iron overload
- Hemosiderosis: stored iron does not interfere with organ function vs. hemochromatosis: iron overload associated with organ failure
Microscopic (histologic) images
Hemosiderin, liver, iron stain
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