Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 30 September 2013, last major update June 2005
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
PubMed Search: Iron[title]
- Also called hemosiderin (storage iron granules)
- See also Hales colloidal iron
- Perl’s method (Prussian blue stain): hydrochloric acid releases the protein bound to ferric iron, then potassium ferrocyanide binds with ferric iron to form ferric ferrocyanide, an insoluble blue compound
- Hemosiderin may be present in areas of old hemorrhage or be deposited in tissues with iron overload
- Hemosiderosis: stored iron does not interfere with organ function vs. hemochromatosis: iron overload associated with organ failure
Hemosiderin, liver, iron stain
End of Stains > Iron
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