Stains
Kappa


Topic Completed: 1 June 2005

Revised: 6 March 2019

Copyright: 2003-2015, PathologyOutlines.com, Inc.

PubMed Search: Kappa[title]

Nat Pernick, M.D.
Page views in 2018: 1,593
Page views in 2019 to date: 1,050
Cite this page: Pernick N. Kappa. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainskappa.html. Accessed July 16th, 2019.
Definition / general
  • Type of immunoglobulin light chain
  • Kappa/lamba ratio is usually 2:1
  • Restricted expression of either kappa or lambda suggests monoclonality and a neoplastic process
Microscopic (histologic) images

Images hosted on Pathout server:

Primary localized laryngeal
amyloidosis (kappa-left; lambda-right)

Contributed by Leica Microsystems, Biosytems Division:
myeloma of marrow with ISH staining for kappa (left)
and lambda (right) light chains using Kappa Probe (PB0645),
Lambda Probe (PB0669) and Bond Polymer Refine Detection

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