Topic Completed: 1 June 2005

Minor changes: 6 March 2019

Copyright: 2003-2015,, Inc.

PubMed Search: Kappa[title]

Nat Pernick, M.D.
Page views in 2019: 2,130
Page views in 2020 to date: 1,425
Cite this page: Pernick N. Kappa. website. Accessed August 11th, 2020.
Definition / general
  • Type of immunoglobulin light chain
  • Kappa/lamba ratio is usually 2:1
  • Restricted expression of either kappa or lambda suggests monoclonality and a neoplastic process
Microscopic (histologic) images

Images hosted on Pathout server:

Primary localized laryngeal
amyloidosis (kappa-left; lambda-right)

Contributed by Leica Microsystems, Biosytems Division:
myeloma of marrow with ISH staining for kappa (left)
and lambda (right) light chains using Kappa Probe (PB0645),
Lambda Probe (PB0669) and Bond Polymer Refine Detection

Back to top