Stains & CD markers
Kappa & lambda light chains


Topic Completed: 1 June 2005

Minor changes: 10 September 2021

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PubMed Search: Kappa[title]

Nat Pernick, M.D.
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Cite this page: Pernick N. Kappa & lambda light chains. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainskappa.html. Accessed October 24th, 2021.
Kappa light chains
  • Type of immunoglobulin light chain
  • Kappa/lamba ratio is usually 2:1
  • Restricted expression of either kappa or lambda suggests monoclonality and a neoplastic process
Microscopic (histologic) images

Contributed by Leica Microsystems, Biosystems Division and AFIP images

Myeloma of marrow with ISH staining

Hodgkin lymphoma

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